{"id":"W4327915227","doi":"10.21203/rs.3.rs-2683050/v1","title":"Eye movement defects in KO zebrafish reveals SRPK3 as a causative gene for an X-linked intellectual disability","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba; Manitoba Health","funders":"National Institute of Neurological Disorders and Stroke; Ministry of Oceans and Fisheries; National Research Foundation of Korea; National Research Foundation; Ulverscroft Foundation; National Institute for Health and Care Research","keywords":"Zebrafish; Intellectual disability; Genetics; Gene; Movement (music); Biology; Neuroscience; Art; Aesthetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001718505,0.0003943537,0.0004017731,0.0002021321,0.0001810943,0.0001124248,0.0006639144,0.0005178119,0.00004166204],"category_scores_gemma":[0.002207797,0.0004120637,0.0002228163,0.0003236681,0.0002960935,0.000004259117,0.001945976,0.0007115391,0.00004013538],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002219052,"about_ca_system_score_gemma":0.000545766,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004821786,"about_ca_topic_score_gemma":0.002585783,"domain_scores_codex":[0.9957647,0.0006572776,0.0005109971,0.001515241,0.0006388896,0.0009128755],"domain_scores_gemma":[0.9980396,0.0002198306,0.00009204296,0.000973501,0.0004077174,0.0002673185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00148362,0.001730016,0.03656654,0.002120413,0.0003166419,0.00003115271,0.003491287,0.00185876,0.9368936,0.0001032062,0.01083267,0.004572065],"study_design_scores_gemma":[0.003432277,0.006507663,0.6671066,0.0006976865,0.00004033937,0.000002429274,0.004500615,0.001004136,0.2783339,0.02953646,0.006873048,0.001964752],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947124,0.0003784402,0.0001582007,0.0003791634,0.0002148637,0.003414623,0.0004269025,0.00002959871,0.0002858542],"genre_scores_gemma":[0.9933375,0.001043204,0.0004589509,0.0001769309,0.0001083063,0.001738412,0.002019907,0.0001067522,0.001010071],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6585597,"threshold_uncertainty_score":0.9998331,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09160894534085004,"score_gpt":0.4060141198952639,"score_spread":0.3144051745544139,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}