{"id":"W4327918774","doi":"10.1016/j.celrep.2023.112262","title":"Immunodominant surface epitopes power immune evasion in the African trypanosome","year":2023,"lang":"en","type":"article","venue":"Cell Reports","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Institutes of Health; Helderleigh Foundation; Argonne National Laboratory; Paul Scherrer Institut; Academy of Pharmaceutical Sciences; Deutsche Forschungsgemeinschaft; Diamond Light Source","keywords":"Epitope; Evasion (ethics); Immune system; Virology; Immunology; Power (physics); Surface protein; Biology; Antigen; Physics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001428373,0.0001572766,0.0001303055,0.0001682833,0.0001428727,0.0003284753,0.0001173706,0.000232097,0.0007633712],"category_scores_gemma":[0.0001552622,0.00007423379,0.00006869209,0.00009780704,0.0003696666,0.0002165042,0.0003118867,0.0002518261,0.0001471527],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001153561,"about_ca_system_score_gemma":0.00009983755,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002409712,"about_ca_topic_score_gemma":0.0003770395,"domain_scores_codex":[0.9999093,0.00002459619,0.000004675808,0.000009970357,0.00002055404,0.00003093565],"domain_scores_gemma":[0.9999295,0.00001736321,0.00001663054,0.000008801296,0.000009594749,0.00001808994],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001042957,0.00001529802,0.001586553,0.00005225452,0.000002936847,0.0001822984,0.0001065343,0.00005744347,0.990254,0.0004720944,0.00004138501,0.007124784],"study_design_scores_gemma":[0.00008030979,0.001987644,0.09749918,0.0000595085,0.00005317775,0.004651586,0.0009735959,0.001703185,0.8777821,0.002470192,0.01271959,0.00001990157],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954938,0.002291445,0.0006981272,0.00008204144,0.000006562955,0.000004418982,0.00001140433,0.00001225428,0.001399958],"genre_scores_gemma":[0.9986734,0.0006184798,0.000378563,0.00004143914,0.000009433762,0.000001864456,0.00001161474,0.000001947233,0.0002633094],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007633712,"threshold_uncertainty_score":0.002553701,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02313151021694392,"score_gpt":0.2962166736241313,"score_spread":0.2730851634071874,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}