{"id":"W4327933168","doi":"10.1055/s-0042-1760504","title":"Emicizumab prophylaxis for the treatment of people with moderate or mild Hemophilia A without Factor VIII inhibitors: results from the primary analysis of the HAVEN 6 study","year":2023,"lang":"en","type":"article","venue":"Hämostaseologie","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Medicine; Bispecific antibody; Monoclonal antibody; Antibody; Internal medicine; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003749985,0.0002862424,0.0008032297,0.0001513671,0.0002974831,0.00001985438,0.0003422765,0.0001041976,0.00003456561],"category_scores_gemma":[0.000378045,0.0000898619,0.0003556898,0.001785171,0.0003173298,0.0000367621,0.0001247373,0.0001566058,0.000005276199],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000181717,"about_ca_system_score_gemma":0.0004313267,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001791743,"about_ca_topic_score_gemma":0.002331782,"domain_scores_codex":[0.9977418,0.0002163553,0.0005217153,0.0004748949,0.0006546202,0.0003906416],"domain_scores_gemma":[0.9959127,0.002226721,0.0002388768,0.001305873,0.0002438962,0.00007198023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.05369049,0.005769578,0.8582463,0.0001521665,0.01806237,0.0001228479,0.03769653,0.001274065,0.003415172,0.000007252803,0.003723474,0.01783982],"study_design_scores_gemma":[0.01819762,0.01515184,0.9114015,0.0001502531,0.006812724,0.000004087248,0.01296305,0.005770783,0.028438,0.00004609905,0.0007865449,0.0002775254],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9877882,0.0003161907,0.00001209342,0.004866522,0.00007265801,0.004830099,0.002009841,0.00005345073,0.0000509743],"genre_scores_gemma":[0.9961757,0.0002936047,0.0001202939,0.00005725834,0.00009435452,0.0004562075,0.0003867878,0.00002857435,0.002387217],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05315522,"threshold_uncertainty_score":0.3664462,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08993517565796683,"score_gpt":0.3437106359401496,"score_spread":0.2537754602821828,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}