{"id":"W4327969692","doi":"10.3390/toxins15030228","title":"The Mycotoxin De-Epoxy-Deoxynivalenol (DOM-1) Increases Endoplasmic Reticulum Stress in Ovarian Theca Cells","year":2023,"lang":"en","type":"article","venue":"Toxins","topic":"Mycotoxins in Agriculture and Food","field":"Agricultural and Biological Sciences","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Universidad Nacional Autónoma de México","keywords":"Unfolded protein response; XBP1; Endoplasmic reticulum; ATF6; Theca; CHOP; Cell biology; Autophagy; Biology; Internal medicine; Endocrinology; Chemistry; Apoptosis; Ovary; Biochemistry; Gene; Medicine; RNA splicing","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000145593,0.0002234756,0.0003361616,0.0001612094,0.0001559892,0.0003080904,0.00008825317,0.0002685097,0.001035557],"category_scores_gemma":[0.000135269,0.0001075089,0.0002673214,0.0001537994,0.0001606731,0.0002157539,0.0001824435,0.0003804125,0.0001816338],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002556708,"about_ca_system_score_gemma":0.0001793791,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007550674,"about_ca_topic_score_gemma":0.001064905,"domain_scores_codex":[0.9998894,0.00002045164,0.00001145893,0.00002815421,0.00002317409,0.00002738628],"domain_scores_gemma":[0.9998931,0.00002864531,0.0000304624,0.00001343983,0.00001430437,0.00002004081],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002136194,0.00001978604,0.0002995671,0.00004485181,0.000003443244,0.00003920934,0.00001751517,0.00001420282,0.9986308,0.00001287048,0.00001561119,0.0006884721],"study_design_scores_gemma":[0.00003470263,0.0007931117,0.02074015,0.00001308898,0.00002403595,0.0002523129,0.0001053007,0.0002591446,0.9750741,0.00002901594,0.002669774,0.000005184451],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935542,0.004179013,0.0008265712,0.0001212022,0.00005743645,0.00002246995,0.0002522155,0.00002235366,0.0009645688],"genre_scores_gemma":[0.9946151,0.002141514,0.0009823503,0.0001175746,0.00001959896,0.0000229909,0.0003304298,0.000008197314,0.001762231],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001035557,"threshold_uncertainty_score":0.003464341,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01163676860628633,"score_gpt":0.2098417576899235,"score_spread":0.1982049890836372,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}