{"id":"W4327980509","doi":"10.1080/27694127.2023.2188523","title":"Atg8 family proteins, LIR/AIM motifs and other interaction modes","year":2023,"lang":"en","type":"article","venue":"Autophagy Reports","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":94,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Structural Genomics Consortium; H2020 European Research Council; Core Research for Evolutional Science and Technology; Wellcome Trust; Cancer Research UK; Biotechnology and Biological Sciences Research Council; Austrian Science Fund; Norges Forskningsråd; Genentech; National Natural Science Foundation of China; Ministry of Education, Culture, Sports, Science and Technology; Japan Agency for Medical Research and Development; McGill University; Deutsche Forschungsgemeinschaft; European Commission; Genome Canada; Ontario Genomics Institute; Francis Crick Institute; European Federation of Pharmaceutical Industries and Associations; Merck KGaA; Japan Society for the Promotion of Science; Directorate for Biological Sciences; Ontario Genomics; Medical Research Council; Bayer; Pfizer; Bristol-Myers Squibb","keywords":"ATG8; Protein–protein interaction; Computational biology; Docking (animal); Biology; Structural motif; Protein family; Autophagy; Cell biology; Chemistry; Genetics; Gene; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002429591,0.0001979799,0.000299511,0.0001664037,0.00009987685,0.00003938005,0.00004101122,0.0001228585,0.0001953379],"category_scores_gemma":[0.00006022055,0.0001690574,0.0001076777,0.0002642775,0.0000763222,0.0001692773,0.00005033839,0.0001707108,0.0001445824],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004344295,"about_ca_system_score_gemma":0.00009528589,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001420491,"about_ca_topic_score_gemma":0.000003164869,"domain_scores_codex":[0.9985698,0.0000338168,0.0003866044,0.0004337907,0.0002871501,0.000288861],"domain_scores_gemma":[0.9990768,0.00003379071,0.0001682229,0.0004773911,0.00006533338,0.0001785065],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001218236,0.001578059,0.1968217,0.001053434,0.001896171,0.04319119,0.004371398,0.0003073759,0.5519438,0.00470243,0.03323591,0.1596802],"study_design_scores_gemma":[0.002395211,0.000692918,0.6336936,0.0005838825,0.000324037,0.004201145,0.0007572463,0.008422604,0.1305047,0.008750529,0.2088809,0.000793244],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885262,0.001028319,0.000150998,0.0003038574,0.000353111,0.0006036065,0.00000484776,0.0005568067,0.008472229],"genre_scores_gemma":[0.9912386,0.0001342155,0.0001905045,0.001109795,0.0002416891,0.0001125723,0.00003147255,0.00005548418,0.006885647],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4368719,"threshold_uncertainty_score":0.689396,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0302821922477254,"score_gpt":0.3139536063813378,"score_spread":0.2836714141336124,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}