{"id":"W4328048371","doi":"10.1111/dom.15057","title":"Cardiovascular and kidney outcomes with canagliflozin according to type 2 diabetes treatment targets at baseline: Data from the <scp>CANVAS</scp> programme and <scp>CREDENCE</scp>","year":2023,"lang":"en","type":"letter","venue":"Diabetes Obesity and Metabolism","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Hospital; University of Manitoba; NOSM University; McGill University Health Centre","funders":"Janssen Canada; Mitsubishi Tanabe Pharma Corporation","keywords":"Canagliflozin; Medicine; Empagliflozin; Internal medicine; Type 2 diabetes; Nephropathy; Type 2 Diabetes Mellitus; Diabetes mellitus; Diabetic nephropathy; Creatinine; Post-hoc analysis; Kidney disease; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004429352,0.0007344207,0.001952015,0.001303085,0.0003362821,0.00130792,0.000856156,0.001173895,0.001520833],"category_scores_gemma":[0.005690122,0.0003882983,0.003655566,0.002768094,0.0002245039,0.001042538,0.000866449,0.002121962,0.0005337882],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000883491,"about_ca_system_score_gemma":0.0007137355,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008363088,"about_ca_topic_score_gemma":0.01124048,"domain_scores_codex":[0.9968252,0.0007748983,0.0004009527,0.0006014598,0.001075921,0.0003216293],"domain_scores_gemma":[0.9927121,0.001549041,0.002992904,0.0005651762,0.001184412,0.0009962053],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1082698,0.001881121,0.8032705,0.001380045,0.01207603,0.000144535,0.0002035671,0.002146167,0.0004872055,0.0002271568,0.01570025,0.05421359],"study_design_scores_gemma":[0.003274775,0.001944259,0.9893475,0.0001090185,0.002299921,0.00008036757,0.00003228201,0.0005698749,0.0001464923,0.0001249592,0.002030554,0.00003994051],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9023332,0.02047469,0.001140187,0.0006311991,0.000171394,0.0006155105,0.06758385,0.0001534926,0.006896537],"genre_scores_gemma":[0.918708,0.003142997,0.001058073,0.0006972401,0.0002930435,0.0005677395,0.07402071,0.00003793915,0.001474212],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008363088,"threshold_uncertainty_score":0.02342492,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03139839481673808,"score_gpt":0.2413543484380646,"score_spread":0.2099559536213265,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}