{"id":"W4328049563","doi":"10.1073/pnas.2220728120","title":"Whale shark rhodopsin adapted to deep-sea lifestyle by a substitution associated with human disease","year":2023,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Photoreceptor and optogenetics research","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; RIKEN; Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology","keywords":"Rhodopsin; Deep sea; Pelagic zone; Biology; Whale; Adaptation (eye); Ecology; Fishery; Retinal; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001094929,0.00009774509,0.0001182618,0.0002536805,0.0004532843,0.00007134621,0.00100275,0.00004997357,0.00002652779],"category_scores_gemma":[0.003190364,0.00006671181,0.00004649961,0.002866586,0.0007849339,0.0003348425,0.0001907587,0.0001490644,0.00001049122],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006197183,"about_ca_system_score_gemma":0.00006181194,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006560164,"about_ca_topic_score_gemma":3.354363e-7,"domain_scores_codex":[0.9970183,0.00001937332,0.0002133614,0.0003604242,0.00211093,0.0002775704],"domain_scores_gemma":[0.9992099,0.000207478,0.0001820235,0.00001189162,0.000245561,0.0001431076],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003132551,0.00006289653,0.008987986,0.00001588944,0.000003751555,3.038969e-8,0.00009886685,0.0001672783,0.9811665,0.006989568,0.002447292,0.00002855419],"study_design_scores_gemma":[0.0001772081,0.00007519737,0.08853881,0.00008295274,0.0000058669,7.99419e-7,0.00003359034,0.003047773,0.905223,0.002430438,0.0002869538,0.00009739048],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955731,0.00001763942,0.000001250688,0.001838611,0.00001369536,0.0002945671,0.0001025881,0.00003843434,0.002120123],"genre_scores_gemma":[0.9991582,0.00001302977,0.00005395277,0.0003107326,0.00002729145,0.0000324136,0.000001136981,0.000006407221,0.0003968544],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07955083,"threshold_uncertainty_score":0.3819394,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09167057620049807,"score_gpt":0.3546672292444685,"score_spread":0.2629966530439705,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}