{"id":"W4328052704","doi":"10.1093/bjd/ljad081","title":"Safety of guselkumab in patients with psoriasis with a history of malignancy: 5-year results from the VOYAGE 1 and VOYAGE 2 trials","year":2023,"lang":"en","type":"article","venue":"British Journal of Dermatology","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Probity Medical Research","funders":"Janssen Research and Development; St Vincent's Hospital Melbourne; Pusan National University Hospital; Humboldt-Universität zu Berlin; Janssen Scientific Affairs; Freie Universität Berlin; Pusan National University; Berlin Institute of Health; University of Melbourne","keywords":"Medicine; Malignancy; Psoriasis; Dermatology; Skin cancer; Breast cancer; Cancer; Population; Family history; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005188866,0.0004716361,0.001770071,0.0003705522,0.0004237201,0.001258977,0.0003844542,0.001501502,0.001748586],"category_scores_gemma":[0.003409441,0.000215425,0.002580996,0.0004972353,0.0004279108,0.0009803645,0.0003201334,0.002259202,0.0003423396],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005046903,"about_ca_system_score_gemma":0.0004853848,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006189673,"about_ca_topic_score_gemma":0.001216707,"domain_scores_codex":[0.9985258,0.0008551768,0.0001176604,0.0001197477,0.0001864488,0.0001952726],"domain_scores_gemma":[0.9961559,0.001486701,0.001207858,0.0002683518,0.00028283,0.0005983125],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7446378,0.008142327,0.04728166,0.003251847,0.009302882,0.0004965723,0.0005132348,0.002982258,0.01386273,0.0004164192,0.0031952,0.1659172],"study_design_scores_gemma":[0.2343197,0.3949165,0.3298182,0.0009645617,0.01178512,0.00158939,0.0004596559,0.002526496,0.00627219,0.001075834,0.01611901,0.0001533575],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9500015,0.04335068,0.0008087998,0.0006202105,0.0001918111,0.0003322964,0.001096211,0.00003571676,0.003562848],"genre_scores_gemma":[0.9909813,0.005915407,0.0002739816,0.0005799963,0.0002046895,0.0001492978,0.0009715525,0.000009067916,0.0009147486],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005188866,"threshold_uncertainty_score":0.02744168,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01635308347776333,"score_gpt":0.2109883568400023,"score_spread":0.1946352733622389,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}