{"id":"W4328053735","doi":"10.46747/cfp.6903160","title":"Challenges with new treatments for Alzheimer disease","year":2023,"lang":"en","type":"article","venue":"Canadian Family Physician","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Disease; Alzheimer's disease; Medicine; Bioinformatics; Gerontology; Pathology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02436933,0.0009867351,0.00224734,0.001670163,0.003592251,0.00527708,0.003560886,0.008469296,0.03830893],"category_scores_gemma":[0.03606693,0.0004234934,0.001645201,0.00138613,0.005183859,0.008856982,0.003445382,0.01828124,0.01026543],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.007698386,"about_ca_system_score_gemma":0.03186567,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.04443038,"about_ca_topic_score_gemma":0.1199354,"domain_scores_codex":[0.9899275,0.002858704,0.0009993764,0.0008136907,0.004673812,0.0007268573],"domain_scores_gemma":[0.9520937,0.01789371,0.001556052,0.001318759,0.01994808,0.007189758],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001537563,0.0002035153,0.0003818174,0.001489482,0.00006862584,0.0002343229,0.0002949449,0.0002596732,0.0002630171,0.02265305,0.5937363,0.3802615],"study_design_scores_gemma":[0.00007921518,0.0001179145,0.0004880341,0.002426443,0.00005402491,0.0003405598,0.0004284449,0.0001516438,0.0000641246,0.01485041,0.9809648,0.00003436666],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0005544835,0.2477322,0.001804421,0.7167881,0.01191757,0.00006212945,0.0002911584,0.0002041725,0.0206457],"genre_scores_gemma":[0.01538896,0.5838515,0.01637563,0.3274229,0.04275893,0.0003025187,0.0007297412,0.00019021,0.0129796],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.04443038,"threshold_uncertainty_score":0.1288789,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08876730030563162,"score_gpt":0.319323587938197,"score_spread":0.2305562876325654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}