{"id":"W4328054134","doi":"10.1016/s2213-2600(22)00534-3","title":"Use of digital measurement of medication adherence and lung function to guide the management of uncontrolled asthma (INCA Sun): a multicentre, single-blinded, randomised clinical trial","year":2023,"lang":"en","type":"article","venue":"The Lancet Respiratory Medicine","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"Medical Research Council; Genentech; Institut National Du Cancer; Interreg North-West Europe; Royal College of Surgeons in Ireland; European Commission; Sanofi; Enterprise Ireland; Regeneron Pharmaceuticals; Teva Pharmaceutical Industries; AstraZeneca; Health Research Board; GlaxoSmithKline; Novartis Pharmaceuticals UK Limited; Amgen","keywords":"Medicine; Asthma; Exacerbation; Inhaler; Exhaled nitric oxide; Randomized controlled trial; Clinical trial; Physical therapy; Pulmonary function testing; Internal medicine; Spirometry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004303989,0.002433172,0.006268203,0.0007176324,0.0009312411,0.002029903,0.001577623,0.004995584,0.009291757],"category_scores_gemma":[0.00638682,0.001286772,0.003681343,0.0007397262,0.002559944,0.001981269,0.001163874,0.004746389,0.001229357],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00109505,"about_ca_system_score_gemma":0.00159041,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002132517,"about_ca_topic_score_gemma":0.002311091,"domain_scores_codex":[0.9965298,0.001929454,0.0003214929,0.0006420061,0.0002749875,0.0003023363],"domain_scores_gemma":[0.9960135,0.001650042,0.001025146,0.0003545927,0.000253323,0.0007032932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9903325,0.003355401,0.0002869883,0.0004627471,0.0007053719,0.000008476673,0.00003597832,0.0000756576,0.0002835715,0.00005281853,0.00017293,0.004227574],"study_design_scores_gemma":[0.9647655,0.03342113,0.0007972636,0.0000500589,0.0004684596,0.000008469681,0.00001609759,0.0001738652,0.00007984726,0.00007905765,0.0001246264,0.0000157072],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9741461,0.007169908,0.001548706,0.001263087,0.001908917,0.01012101,0.001011968,0.0001790178,0.002651155],"genre_scores_gemma":[0.9759512,0.002860343,0.003849203,0.001383934,0.001106479,0.01137882,0.0005742495,0.00003471663,0.002860923],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009291757,"threshold_uncertainty_score":0.03108406,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2053833367047954,"score_gpt":0.3851960989494362,"score_spread":0.1798127622446408,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}