{"id":"W4328094137","doi":"10.1016/s2468-1253(23)00063-8","title":"The quest for the ideal NASH biomarker","year":2023,"lang":"en","type":"letter","venue":"The Lancet. Gastroenterology & hepatology","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Medicine; Steatohepatitis; Liver transplantation; Fatty liver; Internal medicine; Liver biopsy; Hepatology; Disease; Biomarker; Gastroenterology; Liver disease; Transplantation; Intensive care medicine; Biopsy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01321184,0.001331288,0.003556135,0.00175037,0.003875205,0.006693168,0.002551485,0.06449011,0.006964953],"category_scores_gemma":[0.04930897,0.001175047,0.002046747,0.0009707758,0.008095101,0.01192533,0.003269979,0.07125729,0.009963296],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.006115607,"about_ca_system_score_gemma":0.006992952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00551412,"about_ca_topic_score_gemma":0.008336532,"domain_scores_codex":[0.9907575,0.003377914,0.001066589,0.0009466201,0.003167116,0.0006841163],"domain_scores_gemma":[0.9639369,0.02198633,0.001223048,0.0009021167,0.006659069,0.005292441],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001070541,0.00005002214,0.0003437986,0.00008924634,0.00002705127,0.0005207722,0.00005425634,0.00009490553,0.0002136898,0.007447828,0.9650053,0.026046],"study_design_scores_gemma":[0.0004445769,0.0001338125,0.000772054,0.001114045,0.00006272749,0.001702285,0.0004687736,0.0007991704,0.0002286285,0.09006216,0.9040912,0.0001204151],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.00007029365,0.004609997,0.0001107301,0.9831858,0.01115374,0.000003345629,0.0000276787,0.00001247089,0.000826073],"genre_scores_gemma":[0.001303272,0.002980641,0.0003857938,0.9370403,0.05658805,0.00002269822,0.0000316472,0.00001535578,0.00163225],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.06449011,"threshold_uncertainty_score":0.06987166,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04363950007866998,"score_gpt":0.3038982881232064,"score_spread":0.2602587880445364,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}