{"id":"W4328130008","doi":"10.1002/jvc2.126","title":"Improvement in general touch avoidance in patients with moderate‐to‐severe genital psoriasis treated with ixekizumab during a 52‐week, randomized, phase 3 clinical trial (IXORA‐Q)","year":2023,"lang":"en","type":"article","venue":"JEADV Clinical Practice","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Probity Medical Research; SKiN Health; Queen's University","funders":"Eli Lilly and Company; American Academy of Dermatology","keywords":"Ixekizumab; Psoriasis; Medicine; Placebo; Randomized controlled trial; Sex organ; Quality of life (healthcare); Internal medicine; Physical therapy; Dermatology; Secukinumab; Nursing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001633911,0.0006657087,0.001385358,0.000194562,0.0003462566,0.0008601,0.0003483222,0.0007176881,0.003815119],"category_scores_gemma":[0.0009696928,0.0003278968,0.001483651,0.0002068763,0.0004355905,0.0005111188,0.0002430868,0.001563378,0.0003900598],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004101273,"about_ca_system_score_gemma":0.0007927314,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006029121,"about_ca_topic_score_gemma":0.001371976,"domain_scores_codex":[0.9994965,0.0002408829,0.00003731192,0.00008375486,0.00004509768,0.00009651458],"domain_scores_gemma":[0.9995518,0.00008780097,0.0001352846,0.00002846501,0.00002913306,0.0001676106],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8790879,0.01917398,0.008713616,0.001243901,0.002047248,0.00009600718,0.000137394,0.0008098308,0.01734153,0.0001408662,0.00281117,0.06839644],"study_design_scores_gemma":[0.7617857,0.2089072,0.02517875,0.00007121876,0.0006917121,0.0001453328,0.00004463247,0.0007909024,0.001095427,0.0001111695,0.001156871,0.00002111673],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930558,0.002634293,0.0002970396,0.000251288,0.0001336597,0.001510565,0.0004734837,0.00007796306,0.001565958],"genre_scores_gemma":[0.9958644,0.0007887922,0.0005785442,0.0004394973,0.000113413,0.0009959982,0.0003933511,0.000006936024,0.0008190326],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003815119,"threshold_uncertainty_score":0.01276284,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04441120760223758,"score_gpt":0.354716591823644,"score_spread":0.3103053842214064,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}