{"id":"W4353015402","doi":"10.1007/s12325-023-02483-4","title":"Ischemic Stroke and Systemic Embolism Among One-and-Done Direct Oral Anticoagulant Users with Non-valvular Atrial Fibrillation","year":2023,"lang":"en","type":"article","venue":"Advances in Therapy","topic":"Atrial Fibrillation Management and Outcomes","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Group for Research in Decision Analysis","funders":"Janssen Scientific Affairs","keywords":"Medicine; Atrial fibrillation; Internal medicine; Cardiology; Stroke (engine); Embolism; Rheumatology; Oral anticoagulant; Anticoagulant; Ischemic stroke; Rivaroxaban; Warfarin; Ischemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000932879,0.0003113808,0.0003756188,0.0004777432,0.000372332,0.0006794345,0.0003914558,0.0004101995,0.002007147],"category_scores_gemma":[0.002219722,0.0002527348,0.0009544384,0.0005196522,0.0001931778,0.0004190095,0.0004829492,0.0005722184,0.0002335601],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002188025,"about_ca_system_score_gemma":0.0003535663,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002640578,"about_ca_topic_score_gemma":0.003489128,"domain_scores_codex":[0.9993292,0.0001520826,0.00007269511,0.0002161488,0.000121988,0.0001079008],"domain_scores_gemma":[0.9983908,0.0002599288,0.0008479621,0.0001581852,0.000126147,0.0002170169],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004263526,0.00005779296,0.9974443,0.00001185524,0.0001369029,0.00003149037,0.0000276588,0.00002813941,0.00008122336,0.00001926596,0.00008395357,0.001651092],"study_design_scores_gemma":[0.00005451202,0.0003209421,0.9986485,0.00001283686,0.0001272811,0.0002098697,0.00006732139,0.0002465315,0.00007602896,0.00005875371,0.0001729292,0.000004563213],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990177,0.0002246711,0.00008705462,0.00003905864,0.000008552563,0.000009609138,0.0003520753,0.000002085034,0.0002591509],"genre_scores_gemma":[0.9988544,0.0001600964,0.00007339867,0.00003452448,0.0000245154,0.00001349264,0.0006089576,0.000001226803,0.0002293237],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002640578,"threshold_uncertainty_score":0.006714582,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03123094527149826,"score_gpt":0.3188026856673539,"score_spread":0.2875717403958556,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}