{"id":"W4353015582","doi":"10.1007/s40121-023-00791-4","title":"The Significance of Epidemic Plasmids in the Success of Multidrug-Resistant Drug Pandemic Extraintestinal Pathogenic Escherichia coli","year":2023,"lang":"en","type":"review","venue":"Infectious Diseases and Therapy","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dynacast (Canada); University of Calgary","funders":"National Institute of Environmental Health Sciences; National Institute of Allergy and Infectious Diseases; Joint Programming Initiative on Antimicrobial Resistance","keywords":"Multiple drug resistance; Pandemic; Microbiology; Medicine; Escherichia coli; Virology; Drug resistance; Plasmid; Pathogenic Escherichia coli; Highly pathogenic; Coronavirus disease 2019 (COVID-19); Biology; Virus; Infectious disease (medical specialty); Gene; Genetics; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006201832,0.0003533229,0.0007787172,0.00005603543,0.0001181845,0.0000362658,0.0004999202,0.0001700778,0.000004481263],"category_scores_gemma":[0.0002237137,0.000201171,0.0003883177,0.0002501124,0.0005220014,0.000004341337,0.00007026851,0.0002105084,0.000001488667],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002287305,"about_ca_system_score_gemma":0.0003095939,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001678484,"about_ca_topic_score_gemma":0.0001986928,"domain_scores_codex":[0.9977588,0.0006009779,0.0007566222,0.0004108161,0.0001800467,0.000292713],"domain_scores_gemma":[0.9979072,0.0007578913,0.0006544645,0.0005496268,0.00007444269,0.00005642211],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001151533,0.0009621016,0.173336,0.01648126,0.001767896,0.00005188602,0.0003074023,0.00004250462,0.02289316,0.000715999,0.0007657962,0.7815245],"study_design_scores_gemma":[0.00438941,0.001818393,0.1487661,0.01396306,0.001581451,0.000116472,0.0007523791,0.0001038479,0.0004969095,0.002061167,0.8233982,0.002552554],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.3390611,0.659825,0.0000114065,0.000006814113,0.0001096132,0.0007350226,0.0002126733,0.00001124723,0.00002702066],"genre_scores_gemma":[0.1994336,0.8001723,0.000007291492,0.0000193819,0.00009878642,0.0001184669,0.00005831861,0.00004170839,0.00005023252],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8226324,"threshold_uncertainty_score":0.8203515,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0265205185792665,"score_gpt":0.3162135976114985,"score_spread":0.289693079032232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}