{"id":"W4353061670","doi":"10.3390/cimb45030171","title":"Origin and Emergence of Microglia in the CNS—An Interesting (Hi)story of an Eccentric Cell","year":2023,"lang":"en","type":"review","venue":"Current Issues in Molecular Biology","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"","keywords":"Microglia; Biology; Neuroscience; Embryonic stem cell; Central nervous system; Immune system; Progenitor cell; Innate immune system; Cell type; Haematopoiesis; Macrophage; Stem cell; Cell; Inflammation; Immunology; Cell biology; Gene; In vitro; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006805155,0.0002737608,0.0007151495,0.0005252026,0.00004070812,0.00001527668,0.000713106,0.0001409292,0.00002037439],"category_scores_gemma":[0.0005595347,0.0002130991,0.00009951644,0.0007302439,0.0001471758,0.00006116393,0.000155735,0.0005364014,0.00001064273],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001409359,"about_ca_system_score_gemma":0.0000767476,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000826805,"about_ca_topic_score_gemma":0.00001324947,"domain_scores_codex":[0.9951859,0.003007758,0.000785465,0.0006299539,0.000146756,0.0002441882],"domain_scores_gemma":[0.9986832,0.0002860356,0.0004806394,0.0004742267,0.00002872122,0.00004720754],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001478018,0.0004609041,0.00004103371,0.009204227,0.000006035347,0.0001567067,0.001205664,0.00004831721,0.5155753,0.01318477,0.00007451377,0.4600278],"study_design_scores_gemma":[0.0008813914,0.001050023,0.00001450342,0.005046252,0.0001742888,0.0001140266,0.0002406968,0.001240861,0.4889968,0.001779504,0.4992861,0.001175539],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.07961266,0.9175906,0.0003372641,0.00002831562,0.001257041,0.001039512,0.00005813804,0.00003879059,0.00003773253],"genre_scores_gemma":[0.006125703,0.993448,0.0001905543,0.00004087561,0.00004627751,0.00004677846,0.00004889636,0.00003456294,0.00001835434],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.4992116,"threshold_uncertainty_score":0.8689929,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1379905180834188,"score_gpt":0.4300987457673819,"score_spread":0.2921082276839632,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}