{"id":"W4353087883","doi":"10.54097/hset.v36i.5685","title":"Advantages and Disadvantages of Car-T Therapy in the Clinical Treatment of Diffuse Large B-Cell Lymphoma (DLBCL)","year":2023,"lang":"en","type":"article","venue":"Highlights in Science Engineering and Technology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Chimeric antigen receptor; CAR T-cell therapy; Medicine; Lymphoma; Cell therapy; Oncology; Chemotherapy; T cell; Cancer; Internal medicine; Immunotherapy; Immunology; Cell; Immune system; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006597453,0.0001104479,0.0003299371,0.0008588102,0.00003353375,0.000006897088,0.0001837357,0.0001022001,0.000002924934],"category_scores_gemma":[0.00008790485,0.00006605376,0.00002889791,0.001589336,0.0006515216,0.00004591556,0.00006401366,0.00009199877,0.000001752053],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003530574,"about_ca_system_score_gemma":0.0000524488,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002472589,"about_ca_topic_score_gemma":0.00001471644,"domain_scores_codex":[0.9989008,0.00002250658,0.0002756329,0.0002745246,0.0002175937,0.0003089327],"domain_scores_gemma":[0.9992747,0.000283493,0.00003876617,0.0003301507,0.00002984428,0.00004302618],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001931592,0.004333148,0.2803973,0.0001255371,0.00003359556,0.0003005958,0.003190469,0.00002132048,0.6020441,0.01433254,0.00001756927,0.09501064],"study_design_scores_gemma":[0.03480491,0.005684464,0.499254,0.0002387742,0.00002778402,0.000155392,0.003751269,0.005639323,0.4138274,0.0005679138,0.03567066,0.0003780702],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972945,0.001185853,0.000007031853,0.001041241,0.0000671793,0.0002695123,0.000005289758,0.00005122778,0.00007814502],"genre_scores_gemma":[0.9810276,0.01862742,0.0001769597,0.000006209499,0.00001615054,0.00002598208,0.000001165246,0.000008829243,0.0001097144],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2188568,"threshold_uncertainty_score":0.2693594,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02415905536245183,"score_gpt":0.3423455755452983,"score_spread":0.3181865201828465,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}