{"id":"W4360104725","doi":"10.1093/cid/ciad164","title":"Factors Associated With Discontinuation of Tuberculosis Preventive Treatment: Post Hoc Analysis of 2 Randomized, Controlled Trials","year":2023,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Tuberculosis Research and Epidemiology","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal Children's Hospital; McGill University Health Centre; Government of Alberta; Ministry of Health; McGill University","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Discontinuation; Medicine; Regimen; Odds ratio; Internal medicine; Confidence interval; Randomized controlled trial; Adverse effect; Tuberculosis; Pediatrics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.07142201,0.003107432,0.01097168,0.00185628,0.0008231076,0.003691059,0.001961287,0.003619661,0.007917162],"category_scores_gemma":[0.1171476,0.001389146,0.02744042,0.002097883,0.001906046,0.004141342,0.00171782,0.004789852,0.0004277588],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001481698,"about_ca_system_score_gemma":0.002255105,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001089638,"about_ca_topic_score_gemma":0.001579035,"domain_scores_codex":[0.9031215,0.0774603,0.007267249,0.006505092,0.003463915,0.002181899],"domain_scores_gemma":[0.8265128,0.1412837,0.01812143,0.008207534,0.003929304,0.001945144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.6768556,0.001002305,0.01568781,0.009133511,0.2855277,0.0002303967,0.0001537058,0.0009948267,0.0005651298,0.0002399435,0.001303324,0.008305627],"study_design_scores_gemma":[0.4551091,0.04255679,0.0519052,0.001856121,0.4328371,0.0003665253,0.0003356946,0.008395792,0.001091344,0.001725405,0.003589266,0.00023175],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8591916,0.08957765,0.01598346,0.001469747,0.004453365,0.01975724,0.005636752,0.0006173807,0.00331274],"genre_scores_gemma":[0.9640288,0.006476412,0.008514175,0.0009844863,0.0007466053,0.01610905,0.001562765,0.0001545764,0.001423025],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07142201,"threshold_uncertainty_score":0.3777202,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1098318858308192,"score_gpt":0.4413753273286581,"score_spread":0.3315434414978389,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}