{"id":"W4360609373","doi":"10.1371/journal.pone.0279991","title":"Characterization of methylation profiles in spontaneous preterm birth placental villous tissue","year":2023,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Preterm Birth and Chorioamnionitis","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; March of Dimes Prematurity Research Center Ohio Collaborative; U.S. Department of Health and Human Services; March of Dimes Foundation; National Institutes of Health; University of Cincinnati; University of Minnesota","keywords":"DNA methylation; Methylation; Placenta; Biology; Gestation; Placentation; Andrology; Gestational age; Pregnancy; Obstetrics; Fetus; Medicine; Gene; Gene expression; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001501412,0.0001039298,0.0001883801,0.0006999276,0.0001216671,0.0002589851,0.0001545081,0.0001670528,0.0009729735],"category_scores_gemma":[0.0005919992,0.0001127367,0.000128698,0.0004128326,0.0001399669,0.00007565581,0.0001940016,0.0001899573,0.0001748655],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009605825,"about_ca_system_score_gemma":0.0001010109,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009807718,"about_ca_topic_score_gemma":0.001624251,"domain_scores_codex":[0.9998552,0.00002127369,0.00001044819,0.00004429912,0.0000418164,0.00002693746],"domain_scores_gemma":[0.9998362,0.00004424602,0.00004676712,0.00001994347,0.00003253889,0.0000202688],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000397533,0.0000179987,0.1153713,0.000231663,0.0001259866,0.000553779,0.0004830409,0.0002549375,0.8654974,0.0002059556,0.0001634983,0.01669694],"study_design_scores_gemma":[0.00001123756,0.0002398975,0.8753093,0.00002895307,0.0001021959,0.003486085,0.0003833953,0.001467666,0.1151065,0.0004834347,0.003366512,0.00001491477],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928255,0.001779967,0.002960139,0.00003094252,0.000005163234,0.00001767928,0.001492305,0.00004152898,0.0008466641],"genre_scores_gemma":[0.995099,0.0007970377,0.001880899,0.00002872687,0.000004874683,0.00003206016,0.001532285,0.00001709507,0.0006079783],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009807718,"threshold_uncertainty_score":0.00325495,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02538635294515166,"score_gpt":0.2419734362237541,"score_spread":0.2165870832786025,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}