{"id":"W4360609907","doi":"10.21203/rs.3.rs-2051344/v1","title":"Astrocytes express aberrant immunoglobulinsas putative gatekeeper of astrocytes to neuronal progenitor conversion","year":2023,"lang":"en","type":"preprint","venue":"Research Square","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"Agentúra na Podporu Výskumu a Vývoja; Institut National de la Santé et de la Recherche Médicale; Agence Nationale de la Recherche; Université de Lille; Equipex; Ministère de l'Enseignement supérieur, de la Recherche et de l'Innovation","keywords":"Progenitor; Progenitor cell; Astrocyte; Antibody; Cell biology; Neuroscience; Biology; Immunology; Central nervous system; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008107371,0.0002897301,0.0002047975,0.0002574106,0.0001970604,0.0004501252,0.0001521528,0.0002529563,0.0009920454],"category_scores_gemma":[0.00008758748,0.0001476022,0.000266875,0.0001815204,0.0001686438,0.000140358,0.000303067,0.0004808932,0.0006430059],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002752458,"about_ca_system_score_gemma":0.0003186715,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008740561,"about_ca_topic_score_gemma":0.001493981,"domain_scores_codex":[0.9998648,0.000006100959,0.000008558435,0.00003427549,0.00005306571,0.00003316459],"domain_scores_gemma":[0.9999177,0.000004501034,0.00002573404,0.00001127108,0.00001665041,0.00002398118],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002653548,0.000004705864,0.000401904,0.00001920843,0.000005207099,0.0001499357,0.00001134884,0.00002327596,0.9984025,0.0001171822,0.00004111746,0.0007969224],"study_design_scores_gemma":[0.000006361473,0.00004621699,0.01231755,0.000008779285,0.00002426238,0.0007612808,0.00005907665,0.0008187104,0.9791252,0.0002115142,0.006615094,0.00000588518],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9775307,0.001531543,0.0143894,0.000106898,0.00005962192,0.00004608385,0.00159778,0.0005426705,0.004195223],"genre_scores_gemma":[0.9830179,0.0009396212,0.006582484,0.0000816057,0.00001003823,0.0000472745,0.001918123,0.00009723438,0.007305701],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009920454,"threshold_uncertainty_score":0.003318787,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1381727458350038,"score_gpt":0.3832345231591177,"score_spread":0.2450617773241139,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}