{"id":"W4360612069","doi":"10.1136/ard-2022-223559","title":"Rituximab versus azathioprine for maintenance of remission for patients with ANCA-associated vasculitis and relapsing disease: an international randomised controlled trial","year":2023,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Vasculitis and related conditions","field":"Medicine","cited_by":117,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital; McMaster University; University of Toronto","funders":"NIHR Cambridge Biomedical Research Centre; National Center for Advancing Translational Sciences; Wellcome Trust; Vasculitis Clinical Research Consortium; Genentech; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Versus Arthritis; University of Cambridge; University of Miyazaki; Ministry of Health, Labour and Welfare; National Institutes of Health; National Center for Research Resources; University of Pennsylvania; Cambridge University Hospitals; National Institute for Health and Care Research","keywords":"Medicine; Rituximab; Azathioprine; Internal medicine; Gastroenterology; Adverse effect; Maintenance therapy; Vasculitis; Surgery; Disease; Lymphoma; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004239062,0.001393987,0.004055106,0.0005293369,0.0004571074,0.001452095,0.001114339,0.002505283,0.005010469],"category_scores_gemma":[0.005641871,0.0006576655,0.003091675,0.0007026859,0.001404213,0.001279556,0.0005712248,0.002413907,0.0005746106],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009406131,"about_ca_system_score_gemma":0.001080714,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009776689,"about_ca_topic_score_gemma":0.001536867,"domain_scores_codex":[0.9969398,0.002099795,0.0002400587,0.0003616902,0.0001570039,0.0002016533],"domain_scores_gemma":[0.9971249,0.001131801,0.00094768,0.000200331,0.0001595679,0.0004358288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9876121,0.001023175,0.0003031095,0.001261987,0.001778017,0.00002556261,0.00002990861,0.0001102124,0.0004291198,0.00008171108,0.0002826089,0.007062487],"study_design_scores_gemma":[0.9833266,0.01396689,0.0007789398,0.0001341548,0.001095419,0.00002652186,0.00001202552,0.0001611713,0.00006711026,0.00007050589,0.000352778,0.000007838323],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9175069,0.06576577,0.001225118,0.001957791,0.002169526,0.005650797,0.0009443597,0.0001552802,0.00462437],"genre_scores_gemma":[0.9777605,0.01154442,0.001575682,0.001518711,0.001173291,0.004523999,0.0005499395,0.00001671542,0.001336745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005010469,"threshold_uncertainty_score":0.02241862,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02803968185622173,"score_gpt":0.3086604674213796,"score_spread":0.2806207855651578,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}