{"id":"W4360617154","doi":"10.22541/au.167954587.70061237/v1","title":"A REVIEW OF THE EPIGENETIC CLOCK: EMERGING BIOMARKERS FOR ASTHMA AND ALLERGIC DISEASE","year":2023,"lang":"en","type":"review","venue":"","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"dNaM; Epigenetics; DNA methylation; CpG site; Disease; Asthma; Allergy; Epigenesis; Medicine; Biomarker; Bioinformatics; Biology; Immunology; Genetics; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007878743,0.001005441,0.001430908,0.002770867,0.0002938395,0.0009612784,0.0009471591,0.001187399,0.004261924],"category_scores_gemma":[0.001489373,0.00033435,0.0006290496,0.002762803,0.0005301711,0.001702226,0.0007779603,0.002065847,0.002174121],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007416243,"about_ca_system_score_gemma":0.001309945,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001366043,"about_ca_topic_score_gemma":0.00217621,"domain_scores_codex":[0.9997236,0.00005806695,0.00004746284,0.00005943088,0.00009027855,0.00002109461],"domain_scores_gemma":[0.9993336,0.000376941,0.00007844269,0.00001480415,0.0001410709,0.00005519327],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.00007798229,0.00005293808,0.0002776044,0.02205715,0.0001144212,0.0001699637,0.00007988894,0.0002974939,0.001311396,0.003352347,0.0579129,0.9142959],"study_design_scores_gemma":[0.00001126146,0.00008954084,0.001057456,0.005251185,0.0001212795,0.0009029215,0.00005226773,0.00007877363,0.0002336324,0.00189747,0.9902804,0.00002374713],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004957216,0.9987026,0.0001093326,0.0003594031,0.000337731,0.000002807843,0.00001988538,0.000006834694,0.0004117126],"genre_scores_gemma":[0.000278646,0.998689,0.0001594467,0.0002420957,0.0002877432,0.000004945384,0.00003073068,0.000001468553,0.0003058072],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004261924,"threshold_uncertainty_score":0.01425749,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04334822370461736,"score_gpt":0.3541770857994251,"score_spread":0.3108288620948078,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}