{"id":"W4360856175","doi":"10.1186/s13075-023-03031-9","title":"Gut dysbiosis is associated with aortic aneurysm formation and progression in Takayasu arteritis","year":2023,"lang":"en","type":"article","venue":"Arthritis Research & Therapy","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"SENSHIN Medical Research Foundation; Japan Society for the Promotion of Science; Core Research for Evolutional Science and Technology; National Cerebral and Cardiovascular Center; Institute of Genetics; Japan Agency for Medical Research and Development","keywords":"Medicine; Dysbiosis; Gut flora; Campylobacter; Internal medicine; Gastroenterology; Aortic aneurysm; Aorta; Cardiology; Immunology; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003804778,0.0002923947,0.0004306994,0.0006172374,0.0005524476,0.0005861904,0.0001959828,0.0003870894,0.001395615],"category_scores_gemma":[0.001414478,0.0002270668,0.0004022618,0.0006377347,0.0003173865,0.0003479273,0.0005143586,0.0005780105,0.0001338686],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000221802,"about_ca_system_score_gemma":0.0001973609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001192439,"about_ca_topic_score_gemma":0.001223759,"domain_scores_codex":[0.9997008,0.00007051409,0.0000418093,0.00006605298,0.0000580859,0.00006277829],"domain_scores_gemma":[0.9987896,0.0001433075,0.0006801351,0.00004670797,0.0001075938,0.0002326944],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003449497,0.00003712382,0.9967745,0.00003571021,0.00005645757,0.0002734528,0.0001031547,0.00002341634,0.0009526034,0.000008322703,0.00004040959,0.001349868],"study_design_scores_gemma":[0.000005586257,0.0001321134,0.9986413,0.00001429533,0.00004753972,0.000706299,0.0001846127,0.00009007836,0.00008146412,0.00001809282,0.00007478036,0.000003758222],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990066,0.0006178939,0.00006153232,0.00002482304,0.000009282782,0.000004305707,0.00007087929,0.000002220067,0.0002023961],"genre_scores_gemma":[0.9995815,0.0001652226,0.0001080237,0.00001049828,0.00001106649,0.000004210482,0.00007556166,9.55197e-7,0.00004292869],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001395615,"threshold_uncertainty_score":0.004668772,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03819672082305828,"score_gpt":0.3571871482147383,"score_spread":0.31899042739168,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}