{"id":"W4360856175","doi":"10.1186/s13075-023-03031-9","title":"Gut dysbiosis is associated with aortic aneurysm formation and progression in Takayasu arteritis","year":2023,"lang":"en","type":"article","venue":"Arthritis Research & Therapy","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"SENSHIN Medical Research Foundation; Japan Society for the Promotion of Science; Core Research for Evolutional Science and Technology; National Cerebral and Cardiovascular Center; Institute of Genetics; Japan Agency for Medical Research and Development","keywords":"Medicine; Dysbiosis; Gut flora; Campylobacter; Internal medicine; Gastroenterology; Aortic aneurysm; Aorta; Cardiology; Immunology; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006625743,0.0001093157,0.0001363824,0.000169671,0.0001928378,0.0000709827,0.0001023866,0.0001285663,0.00002792376],"category_scores_gemma":[0.00005188247,0.00009643495,0.00002408259,0.0004467667,0.0001379188,0.0000171922,0.00006223596,0.0001834469,0.00002852263],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002477597,"about_ca_system_score_gemma":0.00007516625,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004454009,"about_ca_topic_score_gemma":0.000510097,"domain_scores_codex":[0.9985166,0.0002251271,0.0001834423,0.0003084331,0.0002499525,0.0005164199],"domain_scores_gemma":[0.9995057,0.00002604761,0.00003971733,0.0002008434,0.000127947,0.0000997617],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001567023,0.00009316316,0.009329606,0.00001948985,0.00001675085,0.00007550947,0.0006411636,4.680809e-7,0.8079062,0.000009555247,0.005833394,0.175918],"study_design_scores_gemma":[0.01032442,0.007263908,0.7891492,0.001109687,0.000003766056,0.000294307,0.001038891,0.000479424,0.1373272,0.0006431236,0.05159004,0.0007760945],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956824,0.002051158,0.000006519883,0.001582411,0.00002164506,0.0004767657,0.00003020956,0.00002617499,0.000122781],"genre_scores_gemma":[0.9708903,0.02817458,0.00004841652,0.0002892081,0.00003848654,0.00009854809,0.0002479456,0.00002247132,0.0001900772],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7798195,"threshold_uncertainty_score":0.3932503,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03819672082305828,"score_gpt":0.3571871482147383,"score_spread":0.31899042739168,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}