{"id":"W4360874540","doi":"10.1016/j.clgc.2023.03.009","title":"Impact of Concomitant Prostate Cancer Medications on Efficacy and Safety of Relugolix Versus Leuprolide in Men With Advanced Prostate Cancer","year":2023,"lang":"en","type":"article","venue":"Clinical Genitourinary Cancer","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal","funders":"Myovant Sciences","keywords":"Medicine; Enzalutamide; Docetaxel; Concomitant; Prostate cancer; Urology; Testosterone (patch); Internal medicine; Oncology; Prostate; Adverse effect; Cancer; Androgen receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001247167,0.0002703577,0.001156689,0.0001878683,0.0001982245,0.0006379791,0.0002434533,0.000339999,0.001978433],"category_scores_gemma":[0.002803509,0.0001609641,0.001620198,0.0002156585,0.0003612777,0.0007094155,0.0002854129,0.001192851,0.0001487928],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003979637,"about_ca_system_score_gemma":0.0006373485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008214321,"about_ca_topic_score_gemma":0.002663737,"domain_scores_codex":[0.999132,0.0004929097,0.00006284809,0.00008549989,0.00009981337,0.0001268957],"domain_scores_gemma":[0.998493,0.0006989998,0.0003734048,0.00006016765,0.00005617974,0.0003182511],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.7691521,0.003592761,0.06462464,0.0006123731,0.004827624,0.0001266094,0.0001982745,0.001786799,0.004942312,0.0002453045,0.0007215564,0.1491697],"study_design_scores_gemma":[0.05688079,0.4010341,0.5224317,0.0002164777,0.007502269,0.0004762749,0.0004648726,0.003887187,0.003151892,0.0005820427,0.003281278,0.00009118731],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919978,0.006534506,0.00006607203,0.0002103763,0.00008017207,0.00002585491,0.0001196623,0.00001225063,0.000953214],"genre_scores_gemma":[0.9985297,0.0007567283,0.00009113738,0.0001188014,0.00009423184,0.00001068419,0.0001020227,0.000003166454,0.0002934298],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001978433,"threshold_uncertainty_score":0.0066185,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06496777092265317,"score_gpt":0.4589492273900678,"score_spread":0.3939814564674146,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}