{"id":"W4360990089","doi":"10.1101/2023.03.27.534318","title":"A network of CD163 <sup>+</sup> macrophages monitors enhanced permeability at the blood-dorsal root ganglion barrier","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Dorsal root ganglion; Cell biology; Blood–brain barrier; Endothelium; Vascular permeability; Inflammation; Neurovascular bundle; Permeability (electromagnetism); Biology; Transcytosis; Neuroscience; Phagocytosis; Anatomy; Sensory system; Immunology; Pathology; Medicine; Central nervous system; Cell; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001706201,0.0001509596,0.0001941791,0.0003254079,0.0001947101,0.000384835,0.0001009884,0.0002544153,0.0009817114],"category_scores_gemma":[0.00009586554,0.0001022577,0.00008292733,0.0001507243,0.0002181328,0.0001953578,0.0002413404,0.0002930925,0.0003232897],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001868317,"about_ca_system_score_gemma":0.0001416622,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002946488,"about_ca_topic_score_gemma":0.0003064873,"domain_scores_codex":[0.9998838,0.00001448229,0.000007222067,0.000038227,0.00002746624,0.00002884843],"domain_scores_gemma":[0.9999216,0.000006590405,0.00002557389,0.000006790678,0.00001646366,0.00002302558],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001059688,0.000009110341,0.001416217,0.0000231802,0.000003113482,0.00006928354,0.00003209438,0.00006756026,0.9964508,0.0001838467,0.00005261698,0.001586204],"study_design_scores_gemma":[0.00002718322,0.0003087517,0.06303179,0.00003255717,0.00002725229,0.001181081,0.0004436697,0.005172454,0.9247035,0.001133288,0.003925706,0.00001270478],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898991,0.0007779819,0.007623398,0.00007952915,0.00002266103,0.00001703284,0.0003882701,0.0001041912,0.001087778],"genre_scores_gemma":[0.9942069,0.0001804537,0.003708164,0.00005092761,0.00001078843,0.00002103864,0.0002540384,0.00001710641,0.001550549],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009817114,"threshold_uncertainty_score":0.003284156,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02235620693897443,"score_gpt":0.2337278057423121,"score_spread":0.2113715988033377,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}