{"id":"W4360991431","doi":"10.1016/s2665-9913(23)00059-0","title":"Reconciling immunotherapy and autoimmunity: not for the faint of heart","year":2023,"lang":"en","type":"article","venue":"The Lancet Rheumatology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Rheumatoid arthritis; Immune system; Immunotherapy; Cancer; Adverse effect; Immune checkpoint; Cancer immunotherapy; Immunology; Adjuvant; Oncology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0295856,0.001576478,0.005554306,0.002610537,0.003704573,0.01086457,0.003141227,0.02232286,0.01482409],"category_scores_gemma":[0.05163071,0.0009672822,0.001650098,0.001299497,0.02093702,0.03523084,0.009211002,0.04210576,0.007225495],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003645258,"about_ca_system_score_gemma":0.007301969,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001674828,"about_ca_topic_score_gemma":0.003127195,"domain_scores_codex":[0.9878703,0.005419714,0.0009010431,0.001321612,0.003392821,0.001094567],"domain_scores_gemma":[0.936709,0.04118501,0.004013843,0.004855885,0.007664146,0.005571913],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0009155857,0.0003355266,0.00377767,0.00249013,0.0009860988,0.0007274112,0.001297317,0.0005958742,0.001329134,0.2341197,0.5999854,0.1534403],"study_design_scores_gemma":[0.000391036,0.0002646303,0.001808741,0.002709887,0.0003007214,0.0006951883,0.002127159,0.0003633299,0.0003078376,0.4985695,0.4922845,0.0001775203],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0008411747,0.1884731,0.001680065,0.7727606,0.03201418,0.00001017721,0.00009718374,0.00009271462,0.004030875],"genre_scores_gemma":[0.04829331,0.1202658,0.003882096,0.6532391,0.1654528,0.0001050262,0.0001623972,0.0002582014,0.008341249],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.0295856,"threshold_uncertainty_score":0.1564655,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06685285596376572,"score_gpt":0.3337102290731903,"score_spread":0.2668573731094246,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}