{"id":"W4361001720","doi":"10.1128/jvi.01670-22","title":"HIV-1 DNA and Immune Activation Levels Differ for Long-Lived T-Cells in Lymph Nodes, Compared with Peripheral Blood, during Antiretroviral Therapy","year":2023,"lang":"en","type":"article","venue":"Journal of Virology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"National Institute of Allergy and Infectious Diseases; Eli Lilly and Company; Emory University; Center for AIDS Research, Emory University; National Institutes of Health; National Institute of Diabetes and Digestive and Kidney Diseases; National Heart, Lung, and Blood Institute; Gilead Sciences","keywords":"TIGIT; Biology; CD8; Memory T cell; Immunology; CD38; Immune system; Cytotoxic T cell; T cell; Lymph; Cell biology; Medicine; Pathology; In vitro; Stem cell; Genetics; CD34","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001941495,0.0001494476,0.0002924466,0.0003128663,0.0001831372,0.0006086186,0.0001318265,0.0002595757,0.001725787],"category_scores_gemma":[0.0009148795,0.0001238196,0.0000959623,0.0002063141,0.0001611805,0.0003967142,0.0001581707,0.0003561657,0.000244622],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001490688,"about_ca_system_score_gemma":0.0001117157,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000520722,"about_ca_topic_score_gemma":0.0007452793,"domain_scores_codex":[0.9998249,0.00005334997,0.00001350347,0.00004480478,0.00002032385,0.00004303347],"domain_scores_gemma":[0.9997328,0.00008404811,0.00006369139,0.00002429188,0.00003416077,0.00006103205],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01447574,0.0004354622,0.5172646,0.0002083099,0.000167872,0.0008046205,0.001464251,0.000461904,0.4130469,0.0001593402,0.0002449886,0.05126608],"study_design_scores_gemma":[0.00005449821,0.002090595,0.9712598,0.00003397271,0.0001532406,0.001312215,0.001009126,0.000617609,0.02220171,0.0002096739,0.001037486,0.00001995075],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989442,0.0004260334,0.000123724,0.0000108909,0.000004500788,0.000005695827,0.00008086116,0.000005698,0.000398289],"genre_scores_gemma":[0.999012,0.00009990375,0.0001214856,0.00001702289,0.000007318534,0.000009896349,0.0001298734,0.000004770852,0.0005977259],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001725787,"threshold_uncertainty_score":0.005773365,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02356557899652285,"score_gpt":0.266580254080423,"score_spread":0.2430146750839001,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}