{"id":"W4361005591","doi":"10.3390/antiox12040800","title":"Oxidative Stress and Epigenetics: miRNA Involvement in Rare Autoimmune Diseases","year":2023,"lang":"en","type":"review","venue":"Antioxidants","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"FP7 Science in Society; Instituto de Salud Carlos III; Generalitat Valenciana; Arnie Charbonneau Cancer Institute, University of Calgary","keywords":"Oxidative stress; Epigenetics; microRNA; Immunology; Computational biology; Medicine; Biology; Bioinformatics; Genetics; Gene; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001171418,0.0004048962,0.0007494619,0.0001923343,0.00005916438,0.00004515828,0.0002640974,0.0003043918,0.00001851883],"category_scores_gemma":[0.00009110338,0.0003832639,0.0002138916,0.0002456342,0.0001064288,0.000005478244,0.0003562016,0.0001254545,0.00004130734],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004594296,"about_ca_system_score_gemma":0.0002199708,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003227853,"about_ca_topic_score_gemma":0.00008816457,"domain_scores_codex":[0.998091,0.0001898498,0.0005539089,0.0006655917,0.0001714262,0.0003282072],"domain_scores_gemma":[0.9990035,0.00003254673,0.0002873279,0.0005167274,0.00005219661,0.0001076518],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005136729,0.0005741026,0.003832544,0.04209274,0.001277327,0.0001681772,0.00011703,0.00001212853,0.007804197,0.00006672172,0.001748656,0.942255],"study_design_scores_gemma":[0.001091584,0.0001982048,0.0293105,0.03061692,0.0009402501,0.00001420491,0.0001345371,0.0000180411,0.002432873,0.0001621725,0.9335093,0.001571422],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0177663,0.9804786,0.00002008306,0.000006984505,0.0001422452,0.0008170904,0.0007122583,0.00002612667,0.0000302911],"genre_scores_gemma":[0.001974677,0.9949594,0.00005835245,0.000016192,0.0001331876,0.000139648,0.002263899,0.0000852238,0.0003694535],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9406836,"threshold_uncertainty_score":0.999862,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03267512245003704,"score_gpt":0.3152633963028275,"score_spread":0.2825882738527905,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}