{"id":"W4361010814","doi":"10.1016/j.jtct.2023.03.024","title":"Effect of Autograft CD34+ Dose on Outcome in Pediatric Patients Undergoing Autologous Hematopoietic Stem Cell Transplant for Central Nervous System Tumors","year":2023,"lang":"en","type":"article","venue":"Transplantation and Cellular Therapy","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; SickKids Foundation; Hospital for Sick Children; BC Children's Hospital; University of Toronto","funders":"Cancer Moonshot; National Institute of Allergy and Infectious Diseases; Office of Naval Research; Pharmacyclics; Takeda Oncology; Health Resources and Services Administration; National Institutes of Health; MorphoSys; Legend Biotech; Sangamo Therapeutics; Astellas Pharma; Adaptive Biotechnologies; Kiadis Pharma; bluebird bio; TG Therapeutics; Jazz Pharmaceuticals; StemCyte; BeiGene; HistoGenetics; Atara Biotherapeutics; CareDx; Actinium Pharmaceuticals; National Cancer Institute; Gilead Sciences; Swedish Orphan Biovitrum; Omeros Corporation; Vertex Pharmaceuticals; Leukemia and Lymphoma Society; Moonshot Research and Development Program; Sanofi; GlaxoSmithKline; Incyte; Pfizer; National Heart, Lung, and Blood Institute; Novartis Pharmaceuticals Corporation; CSL Behring; Bristol-Myers Squibb; AstraZeneca; Amgen; Mallinckrodt Pharmaceuticals; Astellas Pharma US","keywords":"Medicine; Quartile; Proportional hazards model; CD34; Hematopoietic stem cell transplantation; Autologous stem-cell transplantation; Oncology; Internal medicine; Transplantation; Surgery; Retrospective cohort study; Clinical endpoint; Stem cell; Clinical trial; Confidence interval; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002238016,0.0001265347,0.0002665559,0.0001182083,0.0001361356,0.0002364034,0.0001376393,0.000166373,0.0006560914],"category_scores_gemma":[0.0008975044,0.00003988658,0.0002738449,0.0001952958,0.0001915516,0.0002389348,0.0001640029,0.0004319556,0.00007619346],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003111117,"about_ca_system_score_gemma":0.0002926691,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007916771,"about_ca_topic_score_gemma":0.001368036,"domain_scores_codex":[0.9998934,0.00002951268,0.000008002484,0.00001577797,0.00001524087,0.00003804785],"domain_scores_gemma":[0.9994815,0.0001964781,0.0001244783,0.00002367591,0.00002419368,0.0001496973],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.04317863,0.001613816,0.850793,0.0001093194,0.0004536417,0.002265604,0.0004105167,0.002437477,0.008739404,0.0004454693,0.001065632,0.08848741],"study_design_scores_gemma":[0.0003232954,0.02237158,0.9691477,0.00002572844,0.0003699541,0.00198015,0.0003122812,0.0009929902,0.00273847,0.0002053545,0.00151759,0.00001485105],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988458,0.0005316485,0.0000509609,0.00003921239,0.000008489774,0.000003729746,0.00005322794,0.000002482024,0.0004644729],"genre_scores_gemma":[0.9995316,0.0001902344,0.00002863708,0.00002384406,0.00001211413,0.000003296939,0.0001154853,0.000001241342,0.00009346416],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007916771,"threshold_uncertainty_score":0.002257228,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01324987074449015,"score_gpt":0.2514878160864732,"score_spread":0.2382379453419831,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}