{"id":"W4361017515","doi":"10.1371/journal.pgen.1010684","title":"Sas-Ptp10D shapes germ-line stem cell niche by facilitating JNK-mediated apoptosis","year":2023,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Japan Society for the Promotion of Science; Ministry of Education, Culture, Sports, Science and Technology; Core Research for Evolutional Science and Technology; Takeda Science Foundation; Japan Agency for Medical Research and Development; Institute of Genetics; Naito Foundation","keywords":"Biology; Cell biology; Stem cell; Niche; Stem cell niche; Stem cell factor; Progenitor cell; Ecology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008221687,0.0002184271,0.0001682121,0.0001366156,0.00009265551,0.0002362802,0.0002062753,0.0001951416,0.0007860924],"category_scores_gemma":[0.0000760588,0.0001337302,0.0002107168,0.00006673543,0.0002028803,0.0001728927,0.0002175191,0.0005137961,0.000253959],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000292627,"about_ca_system_score_gemma":0.0002201153,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004432924,"about_ca_topic_score_gemma":0.0006663665,"domain_scores_codex":[0.9999007,0.00001038576,0.00001188727,0.00002284382,0.00003137308,0.00002279984],"domain_scores_gemma":[0.9999192,0.000008198189,0.00002962454,0.00000834369,0.000006931837,0.00002770031],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004408673,0.000008960352,0.0002194186,0.00002014209,0.000002341935,0.00003813228,0.000004540742,0.00006164415,0.9990846,0.00006033895,0.00001578344,0.0004399438],"study_design_scores_gemma":[0.00002040111,0.0001948888,0.005746212,0.000002476812,0.00001026929,0.0003314221,0.00002599523,0.0015133,0.9907606,0.00005218546,0.001338733,0.00000352939],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957355,0.000703843,0.002218068,0.00007453078,0.00001901264,0.00001108883,0.0001872564,0.00007409493,0.0009765264],"genre_scores_gemma":[0.9971398,0.0003762801,0.001126595,0.00003069174,0.000003630858,0.00001118717,0.0002031857,0.000009725051,0.001098872],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007860924,"threshold_uncertainty_score":0.002629757,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01626264993151324,"score_gpt":0.2342513365116459,"score_spread":0.2179886865801327,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}