{"id":"W4361186947","doi":"10.1016/j.hlife.2023.02.001","title":"Emergence of hypervirulent Pseudomonas aeruginosa pathotypically armed with co-expressed T3SS effectors ExoS and ExoU","year":2023,"lang":"en","type":"article","venue":"hLife","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Key Research and Development Program of China Stem Cell and Translational Research; National Key Research and Development Program of China; International Development Research Centre","keywords":"Virulence; Pseudomonas aeruginosa; Type three secretion system; Microbiology; Pathogenicity island; Effector; Biology; Secretion; Pathogen; Gene; Bacteria; Genetics; Immunology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001184487,0.0003992601,0.0003320419,0.0002756591,0.0002284694,0.0005385677,0.0001946698,0.0004248901,0.000821335],"category_scores_gemma":[0.0003317619,0.0001632494,0.000353937,0.0002589483,0.0002787649,0.0003485511,0.0006221048,0.0008509743,0.0002560362],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001707837,"about_ca_system_score_gemma":0.0001787941,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005789925,"about_ca_topic_score_gemma":0.0005199111,"domain_scores_codex":[0.9996307,0.00004225127,0.00003757053,0.00007684383,0.0001138944,0.00009869447],"domain_scores_gemma":[0.999739,0.00004244362,0.00006700871,0.00004063745,0.00003859066,0.00007236432],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005470567,0.00003498576,0.001362387,0.00001575131,0.000005910133,0.000218378,0.0000331589,0.00001798242,0.9975047,0.00004686369,0.00003942451,0.0006657422],"study_design_scores_gemma":[0.00002989233,0.001345814,0.08178619,0.00002122491,0.00006675718,0.005797991,0.0008317996,0.002203471,0.904348,0.000306553,0.003220923,0.00004148999],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998162,0.0001501339,0.0008270985,0.00008190313,0.00001898478,0.00002137184,0.0002260454,0.00003211217,0.0004803012],"genre_scores_gemma":[0.9964939,0.0001365108,0.001319641,0.0001209858,0.00001541342,0.00003684373,0.0006254522,0.0000179733,0.001233309],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000821335,"threshold_uncertainty_score":0.002747595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01142989787861665,"score_gpt":0.2398728781957336,"score_spread":0.228442980317117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}