{"id":"W4361197643","doi":"10.1139/cjpp-2022-0304","title":"A comparative study of acetyl-<scp>l</scp>-carnitine and caloric restriction impact on hippocampal autophagy, apoptosis, neurogenesis, and astroglial function in AlCl<sub>3</sub>-induced Alzheimer’s in rats","year":2023,"lang":"en","type":"article","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Hippocampal formation; Neurogenesis; Neuroprotection; Glial fibrillary acidic protein; Carnitine; Endocrinology; Hippocampus; Internal medicine; Open field; Medicine; Biology; Neuroscience; Immunohistochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001433067,0.0006132208,0.0005711981,0.0006083463,0.0002535027,0.0002047049,0.0002825608,0.0004092345,0.000848973],"category_scores_gemma":[0.0001019567,0.0002510336,0.0003940862,0.0002340068,0.0004920179,0.0004181437,0.0002002579,0.0006836464,0.0001605575],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003004731,"about_ca_system_score_gemma":0.0004790738,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002265122,"about_ca_topic_score_gemma":0.003823029,"domain_scores_codex":[0.9998876,0.000009862437,0.00001185648,0.00002638525,0.00002365984,0.00004077595],"domain_scores_gemma":[0.9998202,0.000009640208,0.00004556763,0.00001727217,0.00002572054,0.0000816104],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.009598746,0.0008631356,0.00143887,0.0001846427,0.00006167187,0.0002509463,0.0001012406,0.00008985587,0.9823864,0.0001366573,0.00009497752,0.004792871],"study_design_scores_gemma":[0.0005647244,0.0253797,0.0410729,0.00003840338,0.0003305586,0.0008692687,0.0003324101,0.0006988095,0.926862,0.0002788437,0.003515494,0.00005682091],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983462,0.000815063,0.0002090651,0.0000481382,0.00001716504,0.00001784779,0.0002016841,0.00001918882,0.0003257139],"genre_scores_gemma":[0.9937605,0.001948953,0.001022248,0.0001134287,0.00001863428,0.00009619554,0.0006334524,0.00001364012,0.002393058],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002265122,"threshold_uncertainty_score":0.004503846,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05196610753697525,"score_gpt":0.346828943108154,"score_spread":0.2948628355711788,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}