{"id":"W4361199601","doi":"10.3390/bios13040434","title":"Surfactant-Assisted Label-Free Fluorescent Aptamer Biosensors and Binding Assays","year":2023,"lang":"en","type":"article","venue":"Biosensors","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Aptamer; Chemistry; Fluorescence; Biosensor; Cuvette; Pulmonary surfactant; Chromatography; Adsorption; Biophysics; Combinatorial chemistry; Biochemistry; Organic chemistry; Molecular biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001997416,0.001747256,0.00176455,0.001264878,0.0004828969,0.0007818189,0.001817178,0.001791596,0.001297001],"category_scores_gemma":[0.002043621,0.000847131,0.001013964,0.001311741,0.0006300993,0.0008514909,0.0007349741,0.001366871,0.001636347],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006807866,"about_ca_system_score_gemma":0.0003949632,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007764887,"about_ca_topic_score_gemma":0.001493677,"domain_scores_codex":[0.9952181,0.001074077,0.0004139173,0.0008094063,0.0022333,0.0002512455],"domain_scores_gemma":[0.9987405,0.0003484685,0.0002098265,0.0001617377,0.0004635301,0.00007605729],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002157635,0.00001416414,0.00003663462,0.0001032618,0.00001048909,0.00002529784,0.00002522831,0.00009474174,0.997336,0.00006755394,0.00003485374,0.002230388],"study_design_scores_gemma":[0.000003884957,0.00008589676,0.0001259028,0.000005027695,0.000009947378,0.0000891454,0.000008392012,0.001287455,0.9972899,0.0000525166,0.001026785,0.00001514253],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.2822232,0.01123486,0.699524,0.0003347812,0.0003148087,0.0008305031,0.0007547217,0.002423605,0.002359442],"genre_scores_gemma":[0.4002992,0.009556996,0.5731562,0.0003685957,0.0001529097,0.001564487,0.00190042,0.0003668941,0.01263444],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.001997416,"threshold_uncertainty_score":0.01056343,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02272957307313799,"score_gpt":0.2796983822924798,"score_spread":0.2569688092193418,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}