{"id":"W4361205476","doi":"10.51731/cjht.2023.608","title":"Formulary Management of Biologics in Plaque Psoriasis","year":2023,"lang":"en","type":"article","venue":"Canadian Journal of Health Technologies","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Ustekinumab; Biosimilar; Medicine; Formulary; Plaque psoriasis; Biologic Agents; Infliximab; Psoriasis; Family medicine; Tumor necrosis factor alpha; Internal medicine; Dermatology; Disease","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001350233,0.0001041925,0.000414818,0.0008835017,0.00008464851,0.000004650738,0.0003994789,0.0003238237,0.00004107743],"category_scores_gemma":[0.0001779868,0.00007789869,0.00008507933,0.0007826695,0.0003048051,0.00003933549,0.00004890192,0.0004065735,0.00001272382],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001185714,"about_ca_system_score_gemma":0.0003346157,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007229564,"about_ca_topic_score_gemma":0.0008002102,"domain_scores_codex":[0.998609,0.000119582,0.0006485312,0.0001180801,0.00002913768,0.0004756887],"domain_scores_gemma":[0.9993448,0.00009734998,0.0002955103,0.0001833989,0.00005705139,0.00002183648],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004862782,0.00003667792,0.01207357,0.0002569267,0.0002077778,0.0002648459,0.0001498101,0.00001310503,0.0008907118,0.01482255,0.01080054,0.9604349],"study_design_scores_gemma":[0.003458765,0.002380345,0.1630296,0.001647681,0.00008753056,0.000403105,0.02234361,0.00001910515,0.03701028,0.0761947,0.6927955,0.0006298238],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6961749,0.1935131,0.000891522,0.1026691,0.003411721,0.0009298552,0.0001968249,0.000339472,0.001873488],"genre_scores_gemma":[0.9938541,0.004223338,0.001607306,0.0001778702,0.000002326556,0.000003338168,0.000004199118,0.000006304915,0.0001211851],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.959805,"threshold_uncertainty_score":0.3176616,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04817312372920696,"score_gpt":0.3170277767699529,"score_spread":0.2688546530407459,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}