{"id":"W4361208567","doi":"10.1101/2023.03.27.534433","title":"Evolution of an alternative genetic code in the <i>Providencia</i> symbiont of the haematophagous leech <i>Haementeria acuecueyetzin</i>","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Leech Biology and Applications","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal Ontario Museum; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; Universidad Nacional Autónoma de México; Hospital for Sick Children; European Commission","keywords":"Biology; Genome; Leech; Providencia; Evolutionary biology; Symbiotic bacteria; Genetics; Lineage (genetic); Zoology; Symbiosis; Bacteria; Gene; Enterobacteriaceae; Escherichia coli","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008447959,0.0003210955,0.0005679631,0.0001698098,0.0001015783,0.00002036509,0.0009183906,0.0003841827,0.000006470733],"category_scores_gemma":[0.0002052221,0.0002184916,0.0001774085,0.0006321095,0.0003432489,0.00005688806,0.0003966544,0.0006558218,0.00001197229],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000246761,"about_ca_system_score_gemma":0.0006479936,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007976281,"about_ca_topic_score_gemma":0.0001383973,"domain_scores_codex":[0.9976029,0.0003245712,0.0007435022,0.0006136845,0.0004030176,0.0003123314],"domain_scores_gemma":[0.9970683,0.0001094234,0.0006525939,0.00170949,0.0003824616,0.00007766439],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00009593565,0.0005571633,0.06629411,0.0005753976,0.0001744409,0.0000497188,0.0001105006,0.00009586901,0.9300396,0.001802,0.0002021894,0.000003021936],"study_design_scores_gemma":[0.0006710548,0.0001258383,0.6070204,0.0006460957,0.0002213621,2.671565e-7,0.00003672417,0.0003375272,0.3904713,0.00006007534,0.0002050855,0.0002042381],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952617,0.0005661713,0.0004665497,0.0007225533,0.0005275538,0.001853133,0.0005146981,0.0000811903,0.000006402431],"genre_scores_gemma":[0.9976342,0.0001449591,0.001191471,0.000279333,0.0001950163,0.0004974921,0.000001371647,0.00005134921,0.000004767693],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5407263,"threshold_uncertainty_score":0.8909829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02294637932331497,"score_gpt":0.2637424725777323,"score_spread":0.2407960932544173,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}