{"id":"W4361226509","doi":"10.1101/2023.03.03.531061","title":"Natural variation in expression of the mitochondrial flavoprotein WAH-1 alters response to cyanide in <i>C. elegans</i>","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Occupational Cancer Research Centre; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Biology; Gene; Genetics; Caenorhabditis elegans; Flavoprotein; Quantitative trait locus; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000205342,0.000396989,0.0002733307,0.0007765035,0.0003558977,0.0003594454,0.000438226,0.0005069349,0.001605559],"category_scores_gemma":[0.0003388631,0.0002350941,0.0004002496,0.000292179,0.0004419282,0.0001268697,0.0003729026,0.0008800279,0.0001973022],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007094053,"about_ca_system_score_gemma":0.0002289599,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007741704,"about_ca_topic_score_gemma":0.01371384,"domain_scores_codex":[0.9997128,0.00002598029,0.00002687166,0.0001113012,0.00006647789,0.00005660935],"domain_scores_gemma":[0.9994728,0.00009635513,0.0001901235,0.00003279919,0.00006673815,0.0001411795],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002468081,0.00006109045,0.002751872,0.00001751004,0.00002519806,0.00004495344,0.00002475866,0.00005424023,0.9962464,0.00002401729,0.00006480336,0.0004384395],"study_design_scores_gemma":[0.00007810979,0.0008621927,0.6518885,0.00002974044,0.0001348461,0.0004713113,0.0002607637,0.002212581,0.3423607,0.00009353913,0.001540528,0.00006703185],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978269,0.00008697806,0.0003324469,0.00004070954,0.00001227825,0.00001969488,0.001359922,0.0000229573,0.0002980702],"genre_scores_gemma":[0.9967496,0.0000721847,0.0007361442,0.0001294201,0.000004338494,0.0000503296,0.001147251,0.00004667209,0.001063896],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007741704,"threshold_uncertainty_score":0.01539326,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00841708808173425,"score_gpt":0.2139136982861296,"score_spread":0.2054966102043954,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}