{"id":"W4361255123","doi":"10.1158/0008-5472.c.6493703.v1","title":"Data from A Genome-Wide Screen in &lt;b&gt;&lt;i&gt;Saccharomyces cerevisiae&lt;/i&gt;&lt;/b&gt; Reveals Altered Transport As a Mechanism of Resistance to the Anticancer Drug Bleomycin","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Polyamine Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Saccharomyces cerevisiae; Mutant; Biology; Mutation; Gene; Molecular biology; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001608474,0.0009982309,0.001518476,0.0002918497,0.0002082915,0.0001136957,0.004604192,0.0006560179,0.000319317],"category_scores_gemma":[0.0003562643,0.0008582252,0.0004281995,0.000698684,0.0002403267,0.00002803257,0.002563569,0.0005370378,0.0001625807],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006400667,"about_ca_system_score_gemma":0.0006653199,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006171313,"about_ca_topic_score_gemma":0.01646413,"domain_scores_codex":[0.9931751,0.0003471122,0.001804252,0.002831431,0.0008231754,0.001018945],"domain_scores_gemma":[0.9922943,0.0001913874,0.0007815693,0.006010989,0.0003306323,0.0003911777],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002700571,0.0002230762,0.0003009256,0.0002686293,0.0005343623,0.00001953801,0.0003188792,0.000131423,0.9522172,0.005275826,0.03992114,0.0005189906],"study_design_scores_gemma":[0.002037878,0.0001109118,0.04701015,0.000871449,0.0008411626,0.000006634825,0.0001527068,0.0002506865,0.1119947,0.01085731,0.8236191,0.002247353],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8624588,0.03899733,0.02806088,0.01206085,0.0009515556,0.006524588,0.04278621,0.0002425589,0.007917275],"genre_scores_gemma":[0.9408947,0.01451901,0.008211209,0.001753726,0.001328003,0.001011877,0.01418026,0.0002428644,0.01785837],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8402225,"threshold_uncertainty_score":0.9993868,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0282433557061596,"score_gpt":0.281555429973139,"score_spread":0.2533120742669794,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}