{"id":"W4361255359","doi":"10.1158/0008-5472.c.6493911.v1","title":"Data from Silencing of Epidermal Growth Factor Receptor Suppresses Hypoxia-Inducible Factor-2–Driven &lt;i&gt;VHL&lt;/i&gt;&lt;sup&gt;−/−&lt;/sup&gt; Renal Cancer","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"National Cancer Institute; Cancer Research Society","keywords":"Carcinogenesis; Small hairpin RNA; Gene silencing; Cancer research; Hypoxia-inducible factors; Epidermal growth factor receptor; Biology; Molecular biology; Cell growth; Cell culture; Chemistry; Cancer; Gene knockdown; Receptor; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003529073,0.0007331941,0.0006607478,0.0007461509,0.0004381489,0.0005895037,0.0004646996,0.000814014,0.01336214],"category_scores_gemma":[0.0002349695,0.0002844211,0.0009820958,0.0005028234,0.0005579691,0.0004555771,0.0003511616,0.002924995,0.003375812],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006882882,"about_ca_system_score_gemma":0.0006956749,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003449751,"about_ca_topic_score_gemma":0.003120608,"domain_scores_codex":[0.9992459,0.00005277983,0.00009345838,0.0001600086,0.000321554,0.0001263772],"domain_scores_gemma":[0.9994859,0.00008333496,0.00006056842,0.00006968304,0.00008565652,0.0002149316],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000354078,0.0002492068,0.0003065152,0.0001481575,0.00003904753,0.0001471417,0.00004607822,0.0001350768,0.9933639,0.0004863833,0.001910622,0.00281379],"study_design_scores_gemma":[0.00008197839,0.0003999393,0.008713798,0.00001198574,0.00004409276,0.0004687716,0.0000891855,0.001170306,0.9696233,0.0001422869,0.01923521,0.00001914563],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"dataset","genre_scores_codex":[0.8721691,0.005416905,0.01905611,0.003251421,0.001494957,0.0003800284,0.06210393,0.002610839,0.03351669],"genre_scores_gemma":[0.8719104,0.002943524,0.01093493,0.001273475,0.00008713407,0.000758683,0.05128745,0.0005543131,0.06025003],"genre_candidate":"dataset","genre_consensus":null,"teacher_disagreement_score":0.01336214,"threshold_uncertainty_score":0.0447008,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05136523089877493,"score_gpt":0.2904418510201324,"score_spread":0.2390766201213574,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}