{"id":"W4361255794","doi":"10.1371/journal.ppat.1011269","title":"The Trypanosoma brucei MISP family of invariant proteins is co-expressed with BARP as triple helical bundle structures on the surface of salivary gland forms, but is dispensable for parasite development within the tsetse vector","year":2023,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"National Institute on Minority Health and Health Disparities; Medical Research Foundation; National Institute of General Medical Sciences; Medical Research Council; Marie Curie; Natural Sciences and Engineering Research Council of Canada; University of Texas at El Paso; Wellcome Trust; University of Dundee","keywords":"Trypanosoma brucei; Biology; Cell biology; Antigenic variation; Virology; Microbiology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001446605,0.0002741561,0.0004258628,0.00006718653,0.0006487767,0.00006791804,0.0005178772,0.0001103726,0.00009470021],"category_scores_gemma":[0.0004729374,0.00011951,0.0001439144,0.0005328946,0.0003674059,0.00006091617,0.00008055765,0.0002956036,0.00004761227],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006643831,"about_ca_system_score_gemma":0.0006487533,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001202339,"about_ca_topic_score_gemma":0.00008576048,"domain_scores_codex":[0.9974143,0.0001270564,0.0005561779,0.0003986954,0.0009596148,0.0005441451],"domain_scores_gemma":[0.9972256,0.0009607538,0.0002619232,0.0010332,0.0003282157,0.000190259],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001945052,0.0003534312,0.001789984,0.0001851941,0.0004696202,0.000009328567,0.002662532,0.00001479169,0.9785336,0.002653183,0.0112233,0.00015995],"study_design_scores_gemma":[0.001924166,0.001358413,0.2511833,0.0001774884,0.0001060821,0.00002634341,0.001763622,0.000584769,0.7313674,0.0006753586,0.01063416,0.0001988875],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9856538,0.0001467904,0.00007376059,0.008437591,0.00002760084,0.003798387,0.001296703,0.0000497887,0.0005155721],"genre_scores_gemma":[0.9955137,0.0001379356,0.001032059,0.0007582504,0.00006695417,0.000593965,0.000154253,0.00005784435,0.001685021],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2493933,"threshold_uncertainty_score":0.4989931,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05035972686674659,"score_gpt":0.3021893163583619,"score_spread":0.2518295894916153,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}