{"id":"W4361255794","doi":"10.1371/journal.ppat.1011269","title":"The Trypanosoma brucei MISP family of invariant proteins is co-expressed with BARP as triple helical bundle structures on the surface of salivary gland forms, but is dispensable for parasite development within the tsetse vector","year":2023,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Trypanosoma species research and implications","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"National Institute on Minority Health and Health Disparities; Medical Research Foundation; National Institute of General Medical Sciences; Medical Research Council; Marie Curie; Natural Sciences and Engineering Research Council of Canada; University of Texas at El Paso; Wellcome Trust; University of Dundee","keywords":"Trypanosoma brucei; Biology; Cell biology; Antigenic variation; Virology; Microbiology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005131541,0.0002970551,0.0001999845,0.0002040723,0.000156103,0.00027989,0.0001127001,0.0001636027,0.001287988],"category_scores_gemma":[0.000115221,0.0001105208,0.0001805473,0.0002609399,0.0001408159,0.0001698355,0.0002292952,0.0002704727,0.0007453852],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000206632,"about_ca_system_score_gemma":0.0001451086,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006327243,"about_ca_topic_score_gemma":0.0006663247,"domain_scores_codex":[0.9999093,0.000009077205,0.000006767643,0.00002400155,0.00003376903,0.00001713436],"domain_scores_gemma":[0.9999189,0.000008249235,0.0000276258,0.000007729349,0.00001442862,0.00002304709],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006966788,0.000006338238,0.001031617,0.00004646834,0.000005505119,0.0001699611,0.00001522163,0.00002574491,0.9963832,0.00007997966,0.00009969866,0.002066585],"study_design_scores_gemma":[0.00002323122,0.0003788206,0.07786383,0.00002261701,0.00005304989,0.003809307,0.0001641472,0.002581524,0.895017,0.0002025398,0.019869,0.00001486394],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897867,0.002214804,0.004041989,0.0001128209,0.00003162796,0.00001686477,0.001441461,0.0001736537,0.002179963],"genre_scores_gemma":[0.9915152,0.0006924839,0.001917324,0.00004528015,0.00001196229,0.00001244868,0.002745017,0.00002828033,0.003032119],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001287988,"threshold_uncertainty_score":0.00430876,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05035972686674659,"score_gpt":0.3021893163583619,"score_spread":0.2518295894916153,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}