{"id":"W4361269231","doi":"10.1002/anie.202300686","title":"Nickel‐Catalyzed Chemoselective Arylation of Amino Alcohols","year":2023,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Catalytic Cross-Coupling Reactions","field":"Chemistry","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Natural Sciences and Engineering Research Council of Canada; Killam Trusts; Dalhousie University","keywords":"Chemoselectivity; Aniline; Aryl; Chemistry; Electrophile; Catalysis; Chloride; Combinatorial chemistry; Organic chemistry; Nickel; Primary (astronomy)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001638575,0.0004809008,0.0001665181,0.000146569,0.0001741145,0.0001672236,0.0002933443,0.0002265667,0.001245383],"category_scores_gemma":[0.0001760293,0.0001370796,0.0001688146,0.0001587517,0.0001591369,0.0002643691,0.0003882554,0.0004281031,0.0006839405],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003245048,"about_ca_system_score_gemma":0.000372664,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001023624,"about_ca_topic_score_gemma":0.003025675,"domain_scores_codex":[0.9998191,0.00001878074,0.00001504982,0.00004443559,0.00004355677,0.00005924121],"domain_scores_gemma":[0.9999511,0.000006433761,0.00001026269,0.000008262997,0.00001277681,0.00001121307],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007649638,0.00002806062,0.0001278444,0.0001394448,0.0000108636,0.0001394198,0.00004504283,0.00019585,0.9907001,0.0006199857,0.0001790765,0.007737843],"study_design_scores_gemma":[0.000003599128,0.00007247805,0.0002854241,0.000004170187,0.000006821385,0.0001250522,0.000009928911,0.0001919244,0.9960509,0.00003962235,0.003206179,0.000004114079],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9275383,0.004128362,0.02385499,0.0001979157,0.0001322902,0.0001247463,0.0005126484,0.0003122646,0.04319847],"genre_scores_gemma":[0.9880983,0.002064782,0.004113047,0.00005500071,0.0000121322,0.00002604279,0.0002786725,0.00002830095,0.005323613],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001245383,"threshold_uncertainty_score":0.004166186,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02153322455478492,"score_gpt":0.294238757255988,"score_spread":0.2727055327012031,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}