{"id":"W4361270506","doi":"10.1001/jamaoncol.2023.0042","title":"Pathologic Complete Response and Clinical Outcomes in Patients With Localized Soft Tissue Sarcoma Treated With Neoadjuvant Chemoradiotherapy or Radiotherapy","year":2023,"lang":"en","type":"article","venue":"JAMA Oncology","topic":"Sarcoma Diagnosis and Treatment","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Cancer Foundation; McGill University","funders":"National Cancer Institute","keywords":"Medicine; Soft tissue sarcoma; Chemoradiotherapy; Radiation therapy; Internal medicine; Hazard ratio; Proportional hazards model; Oncology; Clinical trial; Sarcoma; Surgery; Soft tissue; Confidence interval; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001261132,0.0001556754,0.0004025418,0.0002749756,0.00015301,0.0002526825,0.0002104877,0.0002896641,0.0008284869],"category_scores_gemma":[0.002819794,0.0001125299,0.0003146827,0.0003143498,0.000275961,0.0003959559,0.0002879183,0.0003111941,0.0001323224],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002692285,"about_ca_system_score_gemma":0.0003150771,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002944977,"about_ca_topic_score_gemma":0.0008856196,"domain_scores_codex":[0.9994621,0.0002638327,0.00006504602,0.00006917962,0.00009519322,0.00004464493],"domain_scores_gemma":[0.9980043,0.0006164968,0.001012508,0.00008020703,0.00008191432,0.0002045548],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.008588178,0.0003032932,0.9694565,0.00008555291,0.0001720999,0.00008319431,0.0000489209,0.0004335997,0.001041353,0.00001510885,0.0002813842,0.01949076],"study_design_scores_gemma":[0.000286372,0.004427268,0.9931319,0.00002335766,0.000127758,0.0004450258,0.00006042209,0.0005416601,0.0004899807,0.00004425822,0.0004146277,0.000007410411],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984804,0.0009146663,0.0001131579,0.00006485992,0.000007007985,0.00002360704,0.0001302712,0.000003885131,0.0002621861],"genre_scores_gemma":[0.9993284,0.000151197,0.00009471027,0.00004108116,0.00001674868,0.00002276016,0.0002595766,0.000001042871,0.00008452177],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001261132,"threshold_uncertainty_score":0.006669581,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03960588045100155,"score_gpt":0.3626036190392862,"score_spread":0.3229977385882846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}