{"id":"W4361270506","doi":"10.1001/jamaoncol.2023.0042","title":"Pathologic Complete Response and Clinical Outcomes in Patients With Localized Soft Tissue Sarcoma Treated With Neoadjuvant Chemoradiotherapy or Radiotherapy","year":2023,"lang":"en","type":"article","venue":"JAMA Oncology","topic":"Sarcoma Diagnosis and Treatment","field":"Medicine","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Cancer Foundation; McGill University","funders":"National Cancer Institute","keywords":"Medicine; Soft tissue sarcoma; Chemoradiotherapy; Radiation therapy; Internal medicine; Hazard ratio; Proportional hazards model; Oncology; Clinical trial; Sarcoma; Surgery; Soft tissue; Confidence interval; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006355381,0.0003289258,0.001406514,0.0002691112,0.00006794875,0.00002364144,0.000100572,0.0002948139,0.0001497131],"category_scores_gemma":[0.0002001073,0.000174742,0.0000762553,0.0004980594,0.0003483885,0.00005821382,0.0000317337,0.0002787039,0.00002808958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003106979,"about_ca_system_score_gemma":0.0002012559,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001335736,"about_ca_topic_score_gemma":0.0002305449,"domain_scores_codex":[0.9975371,0.0006119949,0.0005370632,0.0005992257,0.0002527142,0.0004619099],"domain_scores_gemma":[0.9971581,0.001937187,0.0001779718,0.0004278673,0.00008634505,0.0002125006],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.05253068,0.002362682,0.8168621,0.00001270013,0.0002953552,0.005719839,0.0002649922,0.000003255519,0.00006011291,0.000004857373,0.0005231192,0.1213603],"study_design_scores_gemma":[0.06143759,0.02342036,0.893216,0.00006850118,0.0001103559,0.0002090465,0.0001001178,0.000143292,0.00003540943,0.000007638538,0.02104839,0.0002032648],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912842,0.0002508788,0.00003315536,0.00676036,0.00006186795,0.001365943,0.0000349646,0.0001563957,0.00005225441],"genre_scores_gemma":[0.989292,0.0005918175,0.004804464,0.004506131,0.00005857251,0.0002076697,0.0001007184,0.00007017195,0.0003685],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.121157,"threshold_uncertainty_score":0.712577,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03960588045100155,"score_gpt":0.3626036190392862,"score_spread":0.3229977385882846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}