{"id":"W4361277981","doi":"10.1002/adtp.202300005","title":"Non‐Viral Nucleic Acid Delivery System for RNA Therapeutics","year":2023,"lang":"en","type":"article","venue":"Advanced Therapeutics","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver Biotech (Canada)","funders":"","keywords":"Nucleic acid; Drug delivery; Chemistry; RNA; Conjugate; Nanoparticle; Drug; Biochemistry; Nanotechnology; Biology; Gene; Materials science; Pharmacology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002238755,0.0004254727,0.0003329933,0.0002694792,0.0002835209,0.0004121417,0.0003267462,0.0005379044,0.001839137],"category_scores_gemma":[0.000126562,0.0001636757,0.0002951265,0.0001581086,0.0001938672,0.0004970965,0.000313165,0.0005190807,0.00141508],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004671036,"about_ca_system_score_gemma":0.0004876974,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004511831,"about_ca_topic_score_gemma":0.0004209242,"domain_scores_codex":[0.9998127,0.00003321762,0.00001051405,0.00004309713,0.00008206182,0.0000184412],"domain_scores_gemma":[0.9999446,0.00001219149,0.00001404957,0.000003880564,0.00001630301,0.000008930367],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003026162,0.00003158424,0.00004550143,0.0004367144,0.00001327288,0.0001534094,0.00002879315,0.0002405869,0.9790733,0.003056977,0.000589513,0.01630019],"study_design_scores_gemma":[0.00002127649,0.0004522727,0.0003390303,0.0000530188,0.00003964499,0.0005581597,0.00001721679,0.002969183,0.9278012,0.0004756699,0.0672499,0.00002356699],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4522756,0.1720151,0.3266704,0.001671165,0.002403093,0.0009312233,0.0006485224,0.001665542,0.04171928],"genre_scores_gemma":[0.7974831,0.04407256,0.1037557,0.0009407903,0.0003207194,0.0004944401,0.000679684,0.0001333341,0.05211972],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001839137,"threshold_uncertainty_score":0.006152511,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02150008047819845,"score_gpt":0.2791273731334022,"score_spread":0.2576272926552038,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}