{"id":"W4361279352","doi":"10.1182/bloodadvances.2022009117","title":"Longitudinal patient-reported outcomes in patients receiving chimeric antigen receptor T-cell therapy","year":2023,"lang":"en","type":"article","venue":"Blood Advances","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Leukemia and Lymphoma Society","keywords":"Chimeric antigen receptor; Medicine; Receptor; Antigen; Cell therapy; Immunology; Internal medicine; Cell; Immunotherapy; Biology; Immune system; Genetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002594397,0.000245916,0.0004876585,0.0003844858,0.00008920313,0.00002711511,0.0001566036,0.00007860247,0.0009169728],"category_scores_gemma":[0.0001827243,0.0001998009,0.0001378995,0.001156411,0.00007615457,0.000206782,0.00007136869,0.0002722351,0.0001600401],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005168916,"about_ca_system_score_gemma":0.0000791451,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005704966,"about_ca_topic_score_gemma":0.00002265341,"domain_scores_codex":[0.9976259,0.00008580311,0.0004929375,0.0005063396,0.0007068029,0.0005822234],"domain_scores_gemma":[0.9989639,0.0001576997,0.0001679426,0.000433699,0.0001289603,0.0001477928],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003180114,0.0008590913,0.8753192,0.0000335036,0.0001039557,0.00005574287,0.0003370312,0.000009103575,0.02200142,7.731724e-7,0.0001964561,0.1007657],"study_design_scores_gemma":[0.00554917,0.001011564,0.9464741,0.00007776041,0.00001767082,0.000004079433,0.0001576795,0.00001039339,0.02805767,0.00002645922,0.01838813,0.0002252789],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993968,0.001375401,0.000001534812,0.0002277282,0.0004035154,0.000876603,0.000008542205,0.0001874205,0.002951315],"genre_scores_gemma":[0.9905032,0.004818595,0.0003652364,0.0001206356,0.00009119851,0.00008379593,0.00009296433,0.00006176747,0.003862602],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1005404,"threshold_uncertainty_score":0.9999963,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02843453576457187,"score_gpt":0.3165208986222987,"score_spread":0.2880863628577268,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}