{"id":"W4361298322","doi":"10.1002/iub.2722","title":"Rapamycin treatment unmasks a sex‐specific pattern of scar expansion of the infarcted rat heart: The relationship between <scp>mTOR</scp> and <scp>K<sub>ATP</sub></scp> channel","year":2023,"lang":"en","type":"article","venue":"IUBMB Life","topic":"Cardiac Ischemia and Reperfusion","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Heart Institute","funders":"Institute of Gender and Health; Canadian Institutes of Health Research","keywords":"PI3K/AKT/mTOR pathway; Downregulation and upregulation; Phosphorylation; Internal medicine; Endocrinology; Muscle hypertrophy; Protein subunit; Chemistry; Medicine; Biology; Cell biology; Signal transduction; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001223781,0.0003030136,0.0003509501,0.0002509132,0.0001076617,0.0002079943,0.0001445199,0.0002179831,0.001697225],"category_scores_gemma":[0.00008457006,0.0001683086,0.0002205454,0.0001083023,0.0002471214,0.0002078486,0.0001471987,0.0006239961,0.0002453868],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001054397,"about_ca_system_score_gemma":0.0001425962,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002090335,"about_ca_topic_score_gemma":0.0005160128,"domain_scores_codex":[0.999879,0.00001234911,0.00001171318,0.00002908509,0.00002832695,0.00003953351],"domain_scores_gemma":[0.9998222,0.00001682264,0.0000663176,0.00001430131,0.00001591785,0.00006449995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001644565,0.0000177077,0.0001734088,0.00001895179,0.000002768239,0.00003478316,0.000009141258,0.000005091935,0.999046,0.00001745296,0.000009490504,0.0005008225],"study_design_scores_gemma":[0.00001827483,0.001026001,0.02765307,0.00000598208,0.00002123001,0.0003327016,0.00006895015,0.0002836253,0.9699997,0.0000232821,0.0005624293,0.000004698049],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974319,0.0009999438,0.0007433212,0.00005694224,0.00002371348,0.0000130396,0.0001935659,0.00004448008,0.0004932649],"genre_scores_gemma":[0.9953641,0.0008314911,0.001062666,0.0000689093,0.00002853974,0.00005787017,0.0003476402,0.00002534038,0.002213281],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001697225,"threshold_uncertainty_score":0.00567776,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03683447977216464,"score_gpt":0.2661615329818242,"score_spread":0.2293270532096596,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}