{"id":"W4361301343","doi":"10.1126/sciadv.ade5321","title":"Mechanical nanosurgery of chemoresistant glioblastoma using magnetically controlled carbon nanotubes","year":2023,"lang":"en","type":"article","venue":"Science Advances","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; SickKids Foundation; Hospital for Sick Children","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"CD44; Temozolomide; Radiation therapy; Medicine; Cancer research; Glioblastoma; Carbon nanotube; Chemotherapy; Cell; Nanotechnology; Materials science; Internal medicine; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002148418,0.000194347,0.0005134565,0.0003464944,0.0002407174,0.00008813135,0.0006731234,0.00005053465,0.0001317384],"category_scores_gemma":[0.001138785,0.000156774,0.0001041206,0.002246434,0.001469741,0.0006346988,0.0002392289,0.00007011533,0.00007426934],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008259497,"about_ca_system_score_gemma":0.0004760816,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003121988,"about_ca_topic_score_gemma":0.00001485372,"domain_scores_codex":[0.9966522,0.00009304075,0.0006140202,0.0006202084,0.001233389,0.0007871212],"domain_scores_gemma":[0.9983863,0.0004428026,0.0002280172,0.0004540872,0.000297441,0.0001913032],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004161583,0.00006535675,0.0001096666,0.00002731476,0.000002136044,0.00002865248,0.00006235307,0.000886784,0.9970809,0.0004767865,0.000007588531,0.0008362868],"study_design_scores_gemma":[0.0009568615,0.000233751,0.0001307905,0.00006730227,0.00002010404,0.000007587412,0.0002133927,0.008733438,0.988531,0.0008474253,0.00006167722,0.0001966853],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976442,0.0004028313,0.0000557827,0.0001601791,0.0009934449,0.0002761052,0.00001256643,0.0001882221,0.0002666021],"genre_scores_gemma":[0.997353,0.00002147678,0.00240635,0.0000530538,0.00005956434,0.00002267938,3.73827e-7,0.00001543889,0.00006813214],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008549931,"threshold_uncertainty_score":0.6393057,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01258462024556877,"score_gpt":0.2632679958368523,"score_spread":0.2506833755912836,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}