{"id":"W4361301343","doi":"10.1126/sciadv.ade5321","title":"Mechanical nanosurgery of chemoresistant glioblastoma using magnetically controlled carbon nanotubes","year":2023,"lang":"en","type":"article","venue":"Science Advances","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; SickKids Foundation; Hospital for Sick Children","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Hospital for Sick Children","keywords":"CD44; Temozolomide; Radiation therapy; Medicine; Cancer research; Glioblastoma; Carbon nanotube; Chemotherapy; Cell; Nanotechnology; Materials science; Internal medicine; Chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004803723,0.0001918598,0.00009615063,0.0001528387,0.0001316555,0.000100171,0.0001120194,0.0001746122,0.0003374385],"category_scores_gemma":[0.0000492721,0.00006169706,0.0001100016,0.00005891589,0.0001369221,0.00009071377,0.0001461477,0.0001308253,0.00009138344],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002185936,"about_ca_system_score_gemma":0.0001387954,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008081772,"about_ca_topic_score_gemma":0.002128753,"domain_scores_codex":[0.9999644,0.000002834857,0.000001590306,0.000007209161,0.00001583366,0.000008151757],"domain_scores_gemma":[0.9999779,0.000002603472,0.00001150326,0.000001568397,0.000002809398,0.000003579231],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001847033,0.00001103695,0.00005828627,0.00002875008,0.000002648741,0.00003365455,0.000006269179,0.0003207145,0.995956,0.0002146821,0.00009814645,0.00325136],"study_design_scores_gemma":[0.00001347944,0.0002350671,0.001488897,0.000006502052,0.000007308014,0.0001559035,0.000008727932,0.00456759,0.9896617,0.00009070097,0.003757677,0.000006535585],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9756731,0.002824248,0.01713406,0.0002540601,0.0001070474,0.00007524926,0.00009047557,0.0002277849,0.003614127],"genre_scores_gemma":[0.9893118,0.0009886575,0.007828847,0.00009244784,0.00002787494,0.00004658715,0.00005043396,0.00002317122,0.001630342],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008081772,"threshold_uncertainty_score":0.001606941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01258462024556877,"score_gpt":0.2632679958368523,"score_spread":0.2506833755912836,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}