{"id":"W4361813639","doi":"10.1158/1078-0432.c.6530816","title":"Data from Adavosertib with Chemotherapy in Patients with Primary Platinum-Resistant Ovarian, Fallopian Tube, or Peritoneal Cancer: An Open-Label, Four-Arm, Phase II Study","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"AstraZeneca","keywords":"Medicine; Carboplatin; Internal medicine; Neutropenia; Fallopian tube cancer; Gemcitabine; Gastroenterology; Ovarian cancer; Chemotherapy; Fallopian tube; Phases of clinical research; Anemia; Surgery; Cancer; Cisplatin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001854046,0.0007312315,0.001532411,0.0003404884,0.0002634917,0.0007717067,0.0005721817,0.0008999354,0.002824959],"category_scores_gemma":[0.001588561,0.0004161437,0.001498651,0.000543913,0.0005304615,0.000867582,0.0002904348,0.001858706,0.0005486531],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006151792,"about_ca_system_score_gemma":0.0009954444,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006250687,"about_ca_topic_score_gemma":0.001519816,"domain_scores_codex":[0.9991811,0.0004643863,0.000082454,0.00009549283,0.0001042993,0.00007227133],"domain_scores_gemma":[0.9982925,0.0003689031,0.000548506,0.0002024004,0.0001211341,0.0004665217],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"not_applicable","study_design_scores_codex":[0.778423,0.04033697,0.03750016,0.00143368,0.002985272,0.000266473,0.0002097055,0.001897686,0.0274416,0.0001094847,0.004657784,0.1047382],"study_design_scores_gemma":[0.4690856,0.4329844,0.08295064,0.00008825669,0.001794838,0.0004905331,0.00008340689,0.001194143,0.004883622,0.0001286012,0.006261961,0.00005387373],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"dataset","genre_scores_codex":[0.994418,0.002028791,0.0001808159,0.0002591237,0.00007439157,0.0006040965,0.001274044,0.00004239221,0.001118243],"genre_scores_gemma":[0.9935958,0.001117914,0.0004335814,0.0005746984,0.0001393683,0.0005510699,0.00251022,0.00001673494,0.001060584],"genre_candidate":"dataset","genre_consensus":null,"teacher_disagreement_score":0.002824959,"threshold_uncertainty_score":0.009805262,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1322652722463979,"score_gpt":0.3754764589567084,"score_spread":0.2432111867103105,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}