{"id":"W4361813749","doi":"10.1158/1078-0432.c.6531302.v1","title":"Data from FDA Approval Summary: Osimertinib for Adjuvant Treatment of Surgically Resected Non–Small Cell Lung Cancer, a Collaborative Project Orbis Review","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Osimertinib; Medicine; Lung cancer; Internal medicine; Placebo; Population; Oncology; Confidence interval; Adjuvant; Cancer; Adenocarcinoma; Pathology; Alternative medicine; Environmental health","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005941309,0.0007421535,0.001612471,0.002499261,0.0003671943,0.002102529,0.001103214,0.001704065,0.05531716],"category_scores_gemma":[0.01146339,0.0003913633,0.002232888,0.003951676,0.0002243287,0.001099358,0.0005573159,0.00165156,0.01789305],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001862336,"about_ca_system_score_gemma":0.00622602,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005068042,"about_ca_topic_score_gemma":0.01117177,"domain_scores_codex":[0.9969833,0.0008435597,0.0005156803,0.000249803,0.001246461,0.0001611552],"domain_scores_gemma":[0.9901287,0.002085811,0.001829626,0.0003002579,0.005260038,0.0003956561],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001195015,0.00007250495,0.000454953,0.02577991,0.000521895,0.00006760732,0.00004774681,0.0001216493,0.000750198,0.00117605,0.7191665,0.250646],"study_design_scores_gemma":[0.001258199,0.0003740929,0.004021891,0.01131998,0.0009277781,0.0001070448,0.00003366244,0.00005341546,0.0003546929,0.000386966,0.9811406,0.00002163942],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"dataset","genre_scores_codex":[0.005216725,0.5856597,0.001995669,0.03230133,0.009276314,0.006379455,0.1453007,0.0006841791,0.2131859],"genre_scores_gemma":[0.04377057,0.696705,0.004365751,0.03903497,0.00423289,0.0074207,0.09906239,0.0003722805,0.1050355],"genre_candidate":"dataset","genre_consensus":null,"teacher_disagreement_score":0.05531716,"threshold_uncertainty_score":0.1850544,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1169109972223152,"score_gpt":0.4317259799378558,"score_spread":0.3148149827155406,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}