{"id":"W4361825195","doi":"10.1158/1055-9965.c.6514867.v1","title":"Data from Association of Folate-Pathway Gene Polymorphisms with the Risk of Prostate Cancer: a Population-Based Nested Case-Control Study, Systematic Review, and Meta-analysis","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research","funders":"Health Technology Assessment Programme; National Institute for Health and Care Research; Cancer Research UK; Royal Marsden NHS Foundation Trust; National Cancer Research Institute; School of Medicine, Boston University; Medical Research Council; Cancer Research Institute; National Heart, Lung, and Blood Institute; World Cancer Research Fund; U.S. Department of Defense","keywords":"Methylenetetrahydrofolate reductase; Prostate cancer; MTRR; Medicine; Meta-analysis; Internal medicine; Case-control study; Population; Oncology; Cancer; Gastroenterology; Genetics; Gene; Biology; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01268342,0.002075934,0.01316054,0.006306285,0.0008093753,0.003016753,0.001768784,0.001732521,0.004103856],"category_scores_gemma":[0.04411814,0.001274269,0.02180621,0.00920726,0.0007404682,0.001421863,0.001462251,0.001541549,0.0004751064],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002251835,"about_ca_system_score_gemma":0.004530229,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008915542,"about_ca_topic_score_gemma":0.02203048,"domain_scores_codex":[0.9867975,0.004932314,0.004992476,0.001630867,0.001315391,0.0003314905],"domain_scores_gemma":[0.9706543,0.0214333,0.00415341,0.001084701,0.002419233,0.0002549968],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001254268,0.00002837527,0.009249184,0.452155,0.5250422,0.0002127134,0.000143061,0.0003441644,0.0003443027,0.0001600054,0.001401648,0.009665143],"study_design_scores_gemma":[0.0004679211,0.0001061044,0.006618222,0.02960765,0.9599658,0.0001662176,0.00005502009,0.00007985566,0.0001230412,0.0002312724,0.002552973,0.00002593703],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"dataset","genre_scores_codex":[0.007601589,0.9874956,0.0008404693,0.0003168519,0.0002144553,0.0004996945,0.002563624,0.00002568676,0.0004420354],"genre_scores_gemma":[0.2307507,0.7564852,0.00347088,0.002273246,0.0003618334,0.002289695,0.003769686,0.00005451922,0.0005443109],"genre_candidate":"dataset","genre_consensus":null,"teacher_disagreement_score":0.01316054,"threshold_uncertainty_score":0.06707716,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08064238866980221,"score_gpt":0.3442574861984452,"score_spread":0.263615097528643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}