{"id":"W4361947414","doi":"10.1158/1078-0432.c.6530730","title":"Data from Heterogeneity in <i>NECTIN4</i> Expression Across Molecular Subtypes of Urothelial Cancer Mediates Sensitivity to Enfortumab Vedotin","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; Decipher Biosciences (Canada)","funders":"Council for Science, Technology and Innovation; A.P. Giannini Foundation; Svenska Läkaresällskapet; National Institutes of Health; Vetenskapsrådet; Giannini Foundation of Agricultural Economics","keywords":"Bladder cancer; Cancer research; Cancer; Biology; Medicine; Molecular biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004971765,0.0001982417,0.0003379838,0.0004724553,0.0004236888,0.0005966332,0.000244408,0.0003104219,0.001777623],"category_scores_gemma":[0.001004574,0.0001778864,0.0003728323,0.0006032466,0.0005735316,0.0002558739,0.0004021151,0.0005531122,0.0003500074],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003987608,"about_ca_system_score_gemma":0.0003692239,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001746888,"about_ca_topic_score_gemma":0.003747472,"domain_scores_codex":[0.9993865,0.00008706002,0.00006395767,0.0002103926,0.0001588328,0.00009314327],"domain_scores_gemma":[0.9991956,0.000216935,0.0002157266,0.0001578183,0.000117829,0.00009608481],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.002697141,0.0001553091,0.3333,0.0003314943,0.0003038383,0.000283783,0.0005021534,0.000701831,0.6449609,0.0002499677,0.0008860184,0.0156276],"study_design_scores_gemma":[0.0000706541,0.0007848336,0.8826114,0.00002914053,0.0002874562,0.00128819,0.0008207082,0.0009841636,0.1079393,0.0002433628,0.004922446,0.00001838109],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957015,0.0004754358,0.0007829374,0.00009280869,0.000007127512,0.00003159937,0.001951549,0.0000229626,0.000934068],"genre_scores_gemma":[0.9959146,0.0002087905,0.0005219956,0.000126673,0.000006801031,0.00007048043,0.002669525,0.0000185157,0.0004626444],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001777623,"threshold_uncertainty_score":0.005946755,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06401550406487819,"score_gpt":0.3615291636835015,"score_spread":0.2975136596186233,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}