{"id":"W4361947500","doi":"10.1158/1078-0432.c.6530922","title":"Data from Predictive Significance of an Optimized Panel for Basal-like Breast Cancer: Results from the Canadian Cancer Trials Group MA.5 and MA.12 Phase III Clinical Trials","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; McMaster University Medical Centre; Queen's University; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Breast cancer; Basal (medicine); Internal medicine; Anthracycline; Tamoxifen; Nestin; Oncology; Chemotherapy; Medicine; Predictive marker; Endocrinology; Cancer; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03033951,0.001595255,0.002684026,0.0006951695,0.0007627542,0.001500916,0.001573812,0.001295512,0.004077617],"category_scores_gemma":[0.03630651,0.0004770601,0.003893319,0.001801819,0.0008928822,0.001023153,0.0006659085,0.001726089,0.0006772262],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004127193,"about_ca_system_score_gemma":0.007736105,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0749187,"about_ca_topic_score_gemma":0.1706136,"domain_scores_codex":[0.9827065,0.01110553,0.0009824192,0.001270217,0.003253215,0.0006820813],"domain_scores_gemma":[0.9665612,0.01725509,0.006069702,0.003747809,0.004137869,0.002228225],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.648876,0.0009608231,0.1266835,0.00410439,0.03490086,0.0001910341,0.0002858097,0.01061308,0.004908608,0.001288048,0.05443823,0.1127497],"study_design_scores_gemma":[0.1773516,0.03353049,0.6744924,0.0007948746,0.04294524,0.0004292866,0.0001362464,0.007054281,0.003903074,0.00164336,0.05740401,0.0003151777],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7143013,0.07073522,0.008796996,0.009140192,0.0005628775,0.01064212,0.1481403,0.0006813242,0.03699951],"genre_scores_gemma":[0.9318339,0.004973606,0.004831783,0.002736348,0.0003158724,0.004171399,0.04761371,0.0001686326,0.003354672],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0749187,"threshold_uncertainty_score":0.1604526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3138986411890637,"score_gpt":0.4519041742487665,"score_spread":0.1380055330597028,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}