{"id":"W4361952751","doi":"10.1158/1078-0432.c.6527987.v1","title":"Data from Dose-Ranging and Cohort-Expansion Study of Monalizumab (IPH2201) in Patients with Advanced Gynecologic Malignancies: A Trial of the Canadian Cancer Trials Group (CCTG): IND221","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Nausea; Vomiting; Internal medicine; Cohort; Adverse effect; Pharmacodynamics; Gastroenterology; Cervical cancer; Cancer; Pharmacokinetics","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003023169,0.000713696,0.001047287,0.0002129223,0.000546113,0.0006298496,0.0005850981,0.0007853048,0.004257545],"category_scores_gemma":[0.002337186,0.0002827168,0.0009923711,0.0004270896,0.0003824937,0.0005002784,0.0002505427,0.001942863,0.0005641687],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001250968,"about_ca_system_score_gemma":0.002324652,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006813634,"about_ca_topic_score_gemma":0.01812677,"domain_scores_codex":[0.9988944,0.0005833067,0.00006597466,0.0001278653,0.0001944681,0.00013405],"domain_scores_gemma":[0.9981022,0.0004449052,0.0004099034,0.0003235853,0.0002245764,0.0004948298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8647857,0.007300262,0.02183814,0.0007294001,0.002958819,0.0001389519,0.0001865085,0.00176009,0.01071329,0.0002415677,0.01741172,0.07193563],"study_design_scores_gemma":[0.6768615,0.1369728,0.1563002,0.0001234309,0.003137539,0.0003542097,0.00007412912,0.001522547,0.004509963,0.0002781351,0.01979077,0.00007484516],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"dataset","genre_scores_codex":[0.9700084,0.003531781,0.0005783049,0.0009497124,0.000130388,0.003493805,0.01313371,0.00009632869,0.00807758],"genre_scores_gemma":[0.9820678,0.0009689914,0.0007774735,0.0008453971,0.00009293348,0.001976008,0.01044047,0.00002390538,0.002807024],"genre_candidate":"dataset","genre_consensus":null,"teacher_disagreement_score":0.006813634,"threshold_uncertainty_score":0.01598823,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06870367803291696,"score_gpt":0.301156276021991,"score_spread":0.2324525979890741,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}